Home > Offer to Sell > Intermediates > Pharmaceutical intermediates > Dutasteride for anti cancer

Dutasteride for anti cancer

Inquiry
  Post Date: Jan 09,2017
  Expiry Date: Jan 09,2018
  Detailed Description: Cas No. :164656-23-9 Dutasteride

EMAIL: cgf at chembj dot com
Whatsapp: +8615564141272

Synonyms: Dutasteride,Dutasteride(Avodart),Avolve,Dutasteride API
CAS NO: 164656-23-9
MF: C27H30F6N2O2
MW: 528.53
Purity: 99%
Appearance: white powder
Suitable for: Elderly, Adult
State: Solid
Certification: GMP, ISO 9001, USP
Standard: Enterprise standard
Usage: Medicine material. The treatment of prostate hyperplasia.

Description:

Dutasteride (trademark name Avodart) is a dual 5-α reductase inhibitor that inhibits conversion of testosterone to dihydrotestosterone (DHT). Used for benign prostatic hyperplasia; however, it increases the risk of erectile dysfunction and decreased sexual desire.

Dutasteride useful for the symptoms of benign prostatic hyperplasia (BPH); colloquially known as an "enlarged prostate".
In those who are being regularly screened 5-alpha-reductase inhibitor (finasteride and dutasteride) reduce the overall risk of being diagnosed with prostate cancer however there is insufficient data to determine if they have an effect on the risk of death and may increase the chance of more serious cases.
This class of medications increases rates of erectile dysfunction (with between 5% and 9% developing problems after starting their use). This is linked to lower quality of life and can cause stress in relationships. There is also an association with lowered sexual desire. It has been reported that these adverse sexual side effects may persist even after discontinuation of the drug.

The FDA has added a warning to dutasteride about an increased risk of high-grade prostate cancer. While the potential for positive, negative or neutral changes to the potential risk of developing prostate cancer with dutasteride has not been established, evidence has suggested it may temporarily reduce the growth and prevalence of benign prostate tumors, but could also mask the early detection of prostate cancer. The primary area for concern is for patients who may develop prostate cancer whilst taking dutasteride for benign prostatic hyperplasia, which in turn could delay diagnosis and early treatment of the prostate cancer, thereby potentially increasing the risk of these patients developing high-grade prostate cancer.
Dutasteride (Avodart) is a dual 5-a reductase inhibitor that inhibits conversion of testosterone to DHT. It was developed to treat benign prostatic hyperplasia (BPH), which is the enlargement of the prostate.

Bodybuilders have used this compound to protect themselves from hair loss.

Application:

Dutasteride, along with Finasteride is a 5-alpha-Reductase inhibitor which are a group of drugs with anti-androgenic properties which inhibit the conversion of testosterone into dihydrotestosterone (DHT). This is the same chemical found in Proscar and Propecia and is used in the treatment hyperplasia and androgenic alopecia. Because these drugs reduce levels of dihydrotestosterone (DHT) they are used to prevent and treat hairloss. It is most commonly used to treat enlarged prostate glands.

Packing:

Discreet packing ways as your requirement, 100% go through.

Storage:

Store in cool and dry area and keep away from direct sunlight.

Advantage:

Our company is a professional manufacturer leading factory in China in pharmaceutical area for many years, our products have exported to USA,Greece, Spain, UK, Germany, Australia and other countries, and we have got very good feedback from our customers, we had established a long term friendly relations with our customers all over the world, and in some area like Europe and North America, we have our own agent/remailer/distributor who can help us ship our products very fast and safe, and we have stock in there for transferring.

High quality, best price, first-class service, high successful delivery rate, we have stock, so we can delivery quickly at the very day when payment is arrived.
If you want to it , you can contact me freely.



  CAS Registry Number:

164656-23-9

  Synonyms: ;(5alpha,17beta)-n-{2,5-bis(trifluoromethyl)phenyl}-3-oxo-4-azaandrost-l-ene-17-carboxamide;(4aR,6aS,7S,9aS,9bS,11aR)-N-[2,5-bis(trifluoromethyl)phenyl]-4a,6a-dimethyl-2-oxo-2,4a,4b,5,6,6a,7,8,9,9a,9b,10,11,11a-tetradecahydro-1H-indeno[5,4-f]quinoline-7-carboxamide;(4aR,4bS,6aS,7S,9aS,9bS,11aR)-N-[2,5-bis(trifluoromethyl)phenyl]-4a,6a-dimethyl-2-oxo-2,4a,4b,5,6,6a,7,8,9,9a,9b,10,11,11a-tetradecahydro-1H-indeno[5,4-f]quinoline-7-carboxamide;(4aR,6aS,7S)-N-[2,5-bis(trifluoromethyl)phenyl]-4a,6a-dimethyl-2-oxo-2,4a,4b,5,6,6a,7,8,9,9a,9b,10,11,11a-tetradecahydro-1H-indeno[5,4-f]quinoline-7-carboxamide;
  Molecular Formula: C27H30F6N2O2
  Molecular Weight: 528.5297
  Molecular Structure: 164656-23-9 Dutasteride

  Company: Jian Jiage biological technology co, ltd     [ China ]        
  Contact: Lillian
  Tel: +8615564141272
  Fax: 053185826061
  Email: cgf@chembj.com
Disclaimer statement:The information and data included above have been realized by the enterprises and compiled by the staff, and are subject to change without notice to you. The Chemnet makes no warranties or representations whatsoever regarding the facticity, accuracy and validity of such information and data. In order to ensure your interest, we suggest you chose the products posted by our gold suppliers or VIP members.