Emodin 50%,98%
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| Post Date: | Jan 02,2014 |
| Expiry Date: | Jul 01,2014 |
| Detailed Description: |
Cas No. :491-60-1
Quantity: 100Metric Tons Specs:50%,98% Price:100 USD Kilograms Payment Method: T/T Molecular formula:C15H10O5 Molar mass:270.24 g mol−1 Other names:6-methyl-1,3,8-trihydroxyanthraquinone IUPAC name:1,3,8-trihydroxy-6-methylanthracene-9,10-dione Flash Point:304.2 °C CAS.No: 491-60-1 Usage: Antitumor, ameliorate diabetes, anti-cancer, Anti-tussive, purgating Superlist Name Emodin anthrone Chemical name 9(10H)-Anthracenone,1,3,8-trihydroxy-6-methyl Boiling Point: 556.2 °C at 760 mmH g Flash Point:304.2 °C Synonyms:Ant Anthrone,1,3,8-trihydroxy-6-methyl-(6CI,7CI,8CI);Emodin anthrone;Emodin-9-anthrone;Frangula emodin anthrone; Density: 1.4 1.471 g/cm3 Molecular Weight: 256.25 Emodin Anthraquinones represent a large family of compounds having diverse biological properties. Emodin (1,3,8-trihydroxy-6-methylanthraquinone) is a naturally occurring anthraquinone present in the roots and barks of numerous plants, molds, and lichens, and an active ingredient of various Chinese herbs Pharmacology Emodin is being studied as a potential agent that could reduce the impact of type 2 diabetes. It is a potent selective inhibitor of the enzyme 11β-HSD1. In studies in obese mice, emodin limits the effect of glucocorticoids and may therefore ameliorate diabetes and insulin resistance. Pharmacological studies have demonstrated that emodin when isolated from rhubarb exhibits anti-cancer effects on several human cancers including human pancreatic cancer. Emodin in rhubarb extracts may also have neuroprotective properties against glutamate toxicity, but in other studies it seems to increase inflammation and have other possible neurotoxic effects. Aloe-emodin (1,3,8-trihydroxyanthraquinone) is a variety of emodin found in Socotrine, Barbados, and Zanzibar aloes, but not in Natal aloes Main Functions： 1. Anti-tumor: The Emodin has effective restrain to cell proliferation of hepatoma, lung tumor, bladder tumor and so on； 2. Protecting the Liver: Emodin protect the liver damage caused by carbon tetrachloride, and has a effective restrain to the Hepatitis B; 3. Anti-renal fibrosis: Emodin can restrain the division and proliferation of the HRIF. It can also result in the cell death by improving the level of C-MYC protein； 4. Antibiotic Action: Emodin has the inhibitory action of Staphylococcus aureus, Staphylococcus aureus(S. aureus) and Pseudomonas aeruginosa. Cardioprotective effects Moderate drinking of red wine has long been known to reduce the risk of heart disease. This is best known as “the French paradox”. Studies suggest resveratrol in red wine may play an important role in this phenomenon. It achieves the effects by the following functions: (1) Inhibition of vascular cell adhesion molecule expression; (2) Inhibition of vascular smooth muscle cell proliferation; (3) Stimulation of endolethelial nitric oxide synthase (eNOS) Activity; (4) Inhibition of platelet aggregation; (5) Inhibition of LDL per oxidation; The cardioprotective effects of resveratrol are also theorized to be a form of preconditioning—the best method of cardioprotection, rather than direct therapy. Antidiabetic effects Studies have shown resveratrol possesses hypoglycemic and hypolipidemic effects in both streptozotocin (STZ)-induced diabetes rats and STZ-nicotinamide-induced diabetes rats. Resveratrol ameliorates common diabetes symptoms, such as polyphagia, polydipsia, and body weight loss.[68] Other diabetic animal model studies by different researchers have also demonstrated the antidiabetic effects of resveratrol.[32][23][69][70][71][72][73] In human clinical trials, resveratrol has lowered blood sugar levels in both Phase Ib and Phase IIa, conducted by Sirtris Pharmaceuticals, Inc. Other applications Neuroprotective effects Anti-inflammatory effects Effect on testosterone levels Adverse effects and unknowns Studies have found resveratrol intake is inversely associated with breast cancer risk, and acts to slow the progression of breast cancer that has been transplanted into mice. Some studies suggest resveratrol slows the development of blood vessels, which suppresses tumors, but also slows healing. Citing the evidence that resveratrol is estrogen antagonistic, some retailers of resveratrol advise that the compound may interfere with oral contraceptives and that women who are pregnant or intending to become pregnant should not use the product, while others advise that resveratrol should not be taken by children or young adults under 18, as no studies have shown how it affects their natural development. A small study found a single dose of up to 5 g of trans-resveratrol caused no serious adverse effects in healthy volunteers. Occurrences In plants Resveratrol was originally isolated by Takaoka from the roots of hellebore, In grape. In foods Red wine contains between 0.2 and 5.8 mg/L, while white wine has much less, muscadine grapes, peanuts Before sprouting it was in the range of 2.3 to 4.5 μg/g, and after sprouting in the range of 11.7 to 25.7 μg/g depending upon peanut cultivar. Cocoa powder, baking chocolate and dark chocolate also have low levels of resveratrol in normal consumption quantities (0.35 to 1.85 mg/kg). where will be Resveratrol use to ? • Anti-cancer • Effect on cardiovascular system • Antibacterial and antifungal • Nourish and protect liver • Antioxidant and quench free-radicals • Impact on the metabolism of osseous issue |
| CAS Registry Number: | 491-60-1 |
| Company: | Changsha Staherb Natural Ingredients Co.Ltd. [ China ] |
| Contact: | Agnes Dai |
| Tel: | +86-18374838656 |
| Fax: | +86-731-85953715 |
| Email: | agnes@staherb.com |
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