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Erlotinib hydrochloride

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  Post Date: Jun 07,2016
  Expiry Date: Dec 04,2016
  Detailed Description: Cas No. :183319-69-9 Erlotinib hydrochloride Chemical Properties
mp 223-225°C
storage temp. -20°C Freezer
CAS DataBase Reference 183319-69-9(CAS DataBase Reference)


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Erlotinib hydrochloride Usage And Synthesis
Chemical Properties Off-White Solid
Usage Selective epidermal growth factor receptor (EGFR)-tyrosine kinase inhibitor. Antineoplastic
Usage Erlotinib HCl is an HER1/EGFR inhibitor with IC50 of 2 nM.
Usage Erlotinib HCl (OSI-744) is an EGFR inhibitor with IC50 of 2 nM, >1000-fold more sensitive for EGFR than human c-Src or v-Abl. Phase 3.

  CAS Registry Number:

183319-69-9

  Synonyms: ;ERLOTINIB HCL SALT;Erlotinib, Hydrochloride Salt;N-(3-Ethynylphenyl)-6,7-bis(2-methoxyethoxy)-4- Hydrochloride;quinazolinamine, Hydrochloride Salt, OSI 774, Tarceva;N-(3-Ethynylphenyl)-6,7-bis-(2-methoxyethoxy)-quinazolin-4-amine Hydrochloride;[6,7-Bis-(2-methoxy-ethoxy)-quinazolin-4yl]-(3-ethynyl-phenyl)-amine;Tarceva Hydrochloride See E625000;Erlotinib HCl;N-(3-Ethynylphenyl)[6,7-bis(2-methoxyethoxy)quinazolin-4-yl]amine hydrochloride;6,7-Bis(2-methoxyethoxy)-4-(3-ethynylanilino)quinazoline hydrochloride;Erlotinib, OS-774;N-(3-ethynylphenyl)-6,7-bis(2-methoxyethoxy)quinazolin-4-amine;N-(3-ethynylphenyl)-6,7-bis(2-methoxyethoxy)quinazolin-4-amine hydrochloride (1:1);N-(2-chloro-6-methyl-phenyl)-2-[[6-[4-(2-hydroxyethyl)piperazin-1-yl]-2-methyl-pyrimidin-4-yl]amino]thiazole-5-carboxamide;N-(4-ethynylphenyl)-6,7-bis(2-methoxyethoxy)quinazolin-4-amine hydrochloride (1:1);
  Molecular Formula: C22H24ClN3O4
  Molecular Weight: 429.8967
  Molecular Structure: 183319-69-9 Erlotinib hydrochloride

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