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Everolimus

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  Post Date: Feb 04,2015
  Expiry Date: Feb 04,2016
  Detailed Description: Cas No. :159351-69-6 Product name: Everolimus
CAS: 159351-69-6
Molecular formula: C53H83NO14
Molecular weight: 958.232
Description: Everolimus (RAD-001) is the 40-O-(2-hydroxyethyl) derivative of sirolimus and works similarly to sirolimus as an inhibitor of mammalian target of rapamycin (mTOR).
It is currently used as an immunosuppressant to prevent rejection of organ transplants and treatment of renal cell cancer and other tumours. Much research has also been conducted on everolimus and other mTOR inhibitors for use in a number of cancers.
It is marketed by Novartis under the tradenames Zortress (USA) and Certican (Europe and other countries) in transplantation medicine, and Afinitor in oncology. Everolimus also available with Biocon with the brand name of Evertor.

  CAS Registry Number:

159351-69-6

  Synonyms: ;42-O-(2-Hydroxyethyl)-rapamycin;Certica;RAD-001;SDZRAD;Rapamycin, 42-O-(2-hydroxyethyl)-;Certican;CERTICAN(R);(3S,6R,7Z,9R,10R,12R,14S,15E,17Z,19E,21S,23S,26R,27R,34aS)-9,27-dihydroxy-3-{(1R)-2-[(1S,3R,4R)-4-(2-hydroxyethoxy)-3-methoxycyclohexyl]-1-methylethyl}-10,21-dimethoxy-6,8,12,14,20,26-hexamethyl-9,10,12,13,14,21,22,23,24,25,26,27,32,33,34,34a-hexadecahydro-3H-23,27-epoxypyrido[2,1-c][1,4]oxazacyclohentriacontine-1,5,11,28,29(4H,6H,31H)-pentone;
  Molecular Formula: C53H83NO14
  Molecular Weight: 958.2244
  Molecular Structure: 159351-69-6 Everolimus
  Hazard Symbols:  T:;
  Risk Codes: R48/25:;
  Safety Description: S45:;

  Company: AUSMAUCO BIOTECH CO., LIMITED     [ China ]        
  Contact: john
  Tel: +8618060810639
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  Email: plantsale@aus-bio.com
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