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Evista Raloxifene Hydrochloride for anti cancer
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| Post Date: | Jan 09,2017 |
| Expiry Date: | Jan 09,2018 |
| Detailed Description: |
Cas No. :82640-04-8
Evista (Raloxifene Hydrochloride)
EMAIL: cgf at chembj dot com Whatsapp: +8615564141272 CAS No: 82640-04-8 Molecular Formula: C28H29NO4S Molecular Weight: 475.5992 Apperance: White powder Purity: 99% Certification: ISO 9001, USP, BP Specification: USP Uses: For osteoporosis prevention of postmenopausal women Descritpion: Raloxifene (marketed as Evista) is an oral selective estrogen receptor modulator (SERM) that has estrogenic actions on bone and anti-estrogenic actions on the uterus and breast. It is used in the prevention of osteoporosis in postmenopausal women and to reduce the risk of invasive breast cancer in postmenopausal women with osteoporosis and in postmenopausal women at high risk for invasive breast cancer. This drug is different from hormones (including estrogens and progestins). It works by acting like estrogen (as a selective estrogen receptor modulator or SERM) in some parts of the body. Raloxifene helps to preserve bone mass, but it does not affect the breast and uterus like estrogen or relieve symptoms of menopause such as hot flashes. Evista (Raloxifene Hydrochloride) is an estrogen agonist/antagonist, referred to as a selective estrogen receptor modulator (SERM) and belongs to the benzothiophene class of compounds. The biological actions of Raloxifene are largely mediated through binding to estrogen receptors. This binding results in activation of estrogenic pathways in some tissues (Agonism) and and the blockade of estrogenic pathways in other tissues (Antagonism). Application: Raloxifene is indicated for the treatment and prevention of osteoporosis in postmenopausal women. It is also used for reduction of risk and treatment of invasive breast cancer, and it also reduces breast density.For either osteoporosis treatment or prevention, supplemental calcium and/or vitamin D should be added to the diet if daily intake is inadequate. Raloxifene is used to prevent and treat bone loss (osteoporosis) in women after menopause. Maintaining strong bones by slowing bone loss helps to reduce the risk of fractures. Raloxifene may also lower the chance of getting a certain type of breast cancer (invasive) in women after menopause. May prevent or treat corticosteroid-induced bone loss. American College of Rheumatology states that raloxifene can be offered to selected postmenopausal corticosteroid-treated women who refuse hormone replacement therapy or other antiresorptive agents or in whom such therapies are contraindicated. Reduction in the incidence of invasive breast cancer inpostmenopausal women at high risk for developing the disease. Effect comparable to that of tamoxifen in reducing the risk of invasive breast cancer (STAR trial). No effect on the risk of lobular carcinoma in situ or ductal carcinoma in situ (STAR trial). Effect on breast cancer incidence in women with BRCA1 or BRCA2 genetic mutations not established. Not indicated for the treatment of breast cancer or to reduce the risk of recurrence of breast cancer. 1 Not indicated for reduction in the risk of noninvasive breast cancer. Packing: Discreet packing ways as your requirement, 100% go through. Storage: Store in cool and dry area and keep away from direct sunlight. Advantage: 1. Rich experience. Our company is a professional production leading factory in China in pharmaceutical area of many years, our products have exported to Germany, Spain, UK, USA, Australia, Middle East, and so on other country, and we have got very good feedback from our customers, we had Established long friendly relations of cooperation. 2. Great quality, purity and favourable. Good quality is one of our secret success, welcome order the samples, MOQ just 10 grams. 3. Safe and fast delivery. We have stock, so we can delivery quickly at the very day when receive the payment. 4. Good after-sales service. |
| CAS Registry Number: | 82640-04-8 |
| Synonyms: | ;Raloxifene hydrochloride [USAN];6-Hydroxy-2-(p-hydroxyphenyl)benzo(b)thien-3-yl-p-(2-piperidinoethoxy)phenyl ketone, hydrochloride;Evista;Keoxifene hydrochloride;LY 156758;Methanone, (6-hydroxy-2-(4-hydroxyphenyl)benzo(b)thien-3-yl)(4-(2-(1-piperidinyl)ethoxy)phenyl)-, hydrochloride;Raloxifene HCl;UNII-4F86W47BR6;[6-hydroxy-2-(4-hydroxyphenyl)-1-benzothiophen-3-yl]{4-[2-(piperidin-1-yl)ethoxy]phenyl}methanone hydrochloride (1:1);[6-hydroxy-2-(4-hydroxyphenyl)-2,3-dihydro-1-benzothiophen-3-yl][4-(2-piperidin-1-ylethoxy)phenyl]methanone; |
| Molecular Formula: | C28H29NO4S |
| Molecular Weight: | 475.5992 |
| Molecular Structure: | 
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| Company: | Jian Jiage biological technology co, ltd [ China ] |
| Contact: | Lillian |
| Tel: | +8615564141272 |
| Fax: | 053185826061 |
| Email: | cgf@chembj.com |
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