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Exenatide Acetate

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  Post Date: Jan 13,2013
  Expiry Date: Jan 13,2014
  Detailed Description: Cas No. :141758-74-9 Quantity: 1Kilograms
Specs:98%
Molecular Formula：
C184H282N50O60S

Relative Molecular Mass：
4186.63 g/mol

CAS-Number：
141758-74-9

Long-term Storage：
-20 ± 5°C

Synonyms：
Exendin-4

Sequence：
H-His-Gly-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Leu-Ser-Lys-Gln-Met-Glu-Glu-Glu-Ala-Val-Arg-Leu-Phe-Ile-Glu-Trp-Leu-Lys-Asn-Gly-Gly-Pro-Ser-Ser-Gly-Ala-Pro-Pro-Pro-Ser-NH2 acetate salt

Fields of Application：
Diabetes II

Active Substance：
Exendin-4 (exenatide), a 39-amino acid peptide originally isolated from the salivary glands of the Gila monster (Heloderma suspectum), differs from exendin-3 only in two positions close to the N-terminus. Application of exenatide causes an increase in acinar cAMP without stimulating amylase release. As an incretin mimetic, exenatide acts as agonist of the glucagon-like peptide-1 (GLP-1) receptor. As GLP-1, though with prolonged activity, exenatide augments the postprandial production of insulin and suppresses secretion of glucagon. Forthis reason, exenatide has found use as a medication of diabetes II.

  CAS Registry Number:

141758-74-9
  Synonyms: ;H-His-Gly-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Leu-Ser-Lys-Gln-Met-Glu-Glu-Glu-Ala-Val-Arg-Leu-Phe-Ile-Glu-Trp-Leu-Lys-Asn-Gly-Gly-Pro-Ser-Ser-Gly-Ala-Pro-Pro-Pro-Ser-NH2;Exenatide;
  Molecular Formula: C184H282N50O60S
  Molecular Weight: 4186.57
  Molecular Structure: 141758-74-9 exendin-4

  Company: ISPECHEM CO.,LTD     [ China ]        
  Contact: Jeffrey
  Tel: 86-755-27802869
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  Email: jeffrey@ispechem.com
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