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Firocoxib

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  Post Date: Jun 06,2020
  Expiry Date: Jun 06,2021
  Detailed Description: Cas No. :189954-96-9 Quantity: 1Metric Tons
Product Name: Firocoxib
Synonyms: FIROCOXIB;2(5H)-Furanone, 3-(cyclopropylmethoxy)-5,5-dimethyl-4-4-(methylsulfonyl)phenyl-;3-(cyclopropylmethoxy)-5,5-dimethyl-4-(4-methylsulfonylphenyl)furan-2- one;3-(Cyclopropylmethoxy)-5,5-dimethyl-4-[4-(methylsulfonyl)phenyl]-2(5H)-furanone;Equioxx;Equixx;Librens;ML 1785713
CAS: 189954-96-9
MF: C17H20O5S
MW: 336.4
EINECS:
Product Categories: Aromatics;Heterocycles;Intermediates & Fine Chemicals;Pharmaceuticals;Sulfur & Selenium Compounds;THIOCYMETIN
Mol File: 189954-96-9.mol
Firocoxib Chemical Properties
Melting point 78-80°C
Boiling point 563.9±50.0 °C(Predicted)
density 1.31
storage temp. -20?C Freezer
Safety Information
MSDS Information
Firocoxib Usage And Synthesis
Chemical Properties White Solid
Uses antibacterial
Uses A selective cyclooxygenase-2-(COX-2) inhibitor. Anti-inflammatory; analgesic.
Definition ChEBI: An enol ether that is the cyclopropylmethyl ether of 3-hydroxy-5,5-dimethyl-4-[4-(methylsulfonyl)phenyl]furan-2-one. A selective cyclooxygenase 2 inhibitor, it is used in veterinary medicine for the control of pain and inflammation associated with osteoart ritis in horses and dogs.
Brand name Equioxx (Merial).
Veterinary Drugs and Treatments Firocoxib is indicated in dogs and horses for the control of pain and inflammation associated with osteoarthritis. A chewable tablet form for dogs and an oral paste for horses are available.
Like other NSAIDs, firocoxib can be useful for treating fever, pain, and/or inflammation associated with other conditions, postsurgery, trauma, etc.
Firocoxib may also be useful in other species, but information is scant regarding its safety and efficacy. One study in cats (McCann, Rickes et al. 2005) evaluating firocoxib in experimentally induced pyrexia, demonstrated that the drug was effective after a single oral dose in preventing or attenuating pyrexia at all doses studied (0.75 – 3 mg/kg).

  CAS Registry Number:

189954-96-9
  Synonyms: 2(5H)-Furanone, 3-(cyclopropylmethoxy)-5,5-dimethyl-4-4-(methylsulfonyl)phenyl-;3-(cyclopropylmethoxy)-5,5-dimethyl-4-(4-methylsulfonylphenyl)furan-2- one;3-(Cyclopropylmethoxy)-5,5-dimethyl-4-[4-(methylsulfonyl)phenyl]-2(5H)-furanone;3-(cyclopropylmethoxy)-5,5-dimethyl-4-[4-(methylsulfonyl)phenyl]furan-2(5H)-one;
  Molecular Formula: C17H20O5S
  Molecular Weight: 336.4027
  Molecular Structure: 189954-96-9 Firocoxib

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