Fluticasone propionate
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| Post Date: | Mar 16,2014 |
| Expiry Date: | Mar 16,2015 |
| Detailed Description: |
Cas No. :80474-14-2
Quantity: 500Kilograms Price:0.0 USD Kilograms Payment Method: T/T in advance CAS No. 80474-14-2 Chemical Name: Fluticasone propionate Synonyms: Zoflut;flutide;FLUNASE;FLONASE;FLOVENT;cci18781;CUTIVATE;FLIXONASE;FLIXOTIDE;Flutide N CBNumber: CB1252206 Molecular Formula: C25H31F3O5S Formula Weight: 500.57 MOL File: 80474-14-2.mol Fluticasone propionate Property mp : 275 °C refractive index : 31 ° (C=1, Dioxane) storage temp. : Store at RT solubility : DMSO: ≥10 mg/mL form : solid color : white Merck : 4211 CAS DataBase Reference: 80474-14-2(CAS DataBase Reference) Safety Safety Statements : 22-24/25 WGK Germany : 2 RTECS : BV7980000 Fluticasone propionate Chemical Properties,Usage,Production Chemical Properties Crystalline Solid Usage An antiallergic and anti inflammatory Usage A derivative of Flumethasone. An antiallergic; anti-asthmatic; anti-inflammatory. Biological Activity High affinity, selective glucocorticoid receptor agonist (K d = 0.5 nM). Potently stimulates glucocorticoid receptor-mediated transactivation of gene expression and enhances human eosinophil apoptosis (EC 50 = 3.7 nM) in vitro . Inhibits mast cell accumulation in nasal mucosa following topical administration. Lipophilic, clinically-used anti-inflammatory agent with low oral bioavailability. Fluticasone propionate Preparation Products And Raw materials Raw materials 3-METHOXYPROPIONIC ACID Bromofluoromethane Dimethyl sulfide |
| CAS Registry Number: | 80474-14-2 |
| Synonyms: | ;S-Fluoromethyl-6alpha,9alpha-difluoro-11beta-hydroxy-16alpha-methyl-3-oxo-17alpha-propionyloxyandrosta-1,4-diene-17beta-carbothioate; (6a,11b,16a,17a)-6,9-Difluoro-11-hydroxy-16-methyl-3-oxo-17-(1-oxopropoxy)androsta-1,4-diene-17-carbothioic acid S-(fluoromethyl) ester;(6alpha,8xi,11beta,16alpha,17alpha)-6,9-difluoro-17-{[(fluoromethyl)sulfanyl]carbonyl}-11-hydroxy-16-methyl-3-oxoandrosta-1,4-dien-17-yl propanoate;(6alpha,11beta,16alpha,17alpha)-6,9-difluoro-17-{[(fluoromethyl)sulfanyl]carbonyl}-11-hydroxy-16-methyl-3-oxoandrosta-1,4-dien-17-yl propanoate;S-(fluoromethyl) (6alpha,11beta,16alpha,17alpha)-6,9-difluoro-11,17-dihydroxy-16-methyl-3-oxoandrosta-1,4-diene-17-carbothioate; |
| Molecular Formula: | C22H27F3O4S |
| Molecular Weight: | 444.5076 |
| Molecular Structure: | 
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| Safety Description: | S22:; S24/25:; |
| Company: | shanghai run-biotech co., ltd [ China ] |
| Contact: | junyong zhang |
| Tel: | 86-21-61900721 |
| Fax: | 86-13636696795 |
| Email: | jyzhang@run-biotech.com |
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