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Follistatin 334

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  Post Date: Sep 21,2016
  Expiry Date: Sep 21,2017
  Detailed Description: Cas No. :00-00-0 Quantity: 1Kilograms
Specs:alisa@pharm-china.com
Price:1 USD Kilograms
Payment Method: Western Union, MoneyGram, Bank transfer, Bite
Follistatin 334

1. Quick Details:
Follistatin (FST) is a secreted glycoprotein that was first identified as a follicle-stimulating hormone inhibiting substance in ovarian follicular fluid (1, 2). Human Follistatin cDNA encodes a 344 amino acid (aa) protein with a 29 aa signal sequence, an N-terminal atypical TGF binding domain, three Follistatin domains that contain EGF-like and kazal-like motifs, and a highly acidic C-terminal tail. Follistatin is a secreted protein that binds to ligands of the TGF-Beta family and regulates their activity by inhibiting their access to signaling receptors. It was originally discovered as activin antagonists whose activity suppresses expression and secretion of the pituitary hormone FSH (follicle stimulating hormone). In addition to being a natural antagonist, follistatin can inhibit the activity of other TGF-Beta ligands including BMP-2,-4,-6,-7, Myostatin, GDF-11, and TGF-Beta1. Follistatin is expressed in the pituitary, ovaries, decidual cells of the endometrium, and in some other tissues. Recombinant human Follistatin is a 37.8 kDa protein containing 344 amino acids.

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a. Fast Delivery: 3 work days after received payment.
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Raw Powder
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4. More Information About Follistatin 334:

Follistatin (FST) is a secreted glycoprotein that was first identified as a follicle-stimulating hormone inhibiting substance in ovarian follicular fluid (1, 2). Human Follistatin cDNA encodes a 344 amino acid (aa) protein with a 29 aa signal sequence, an N-terminal atypical TGF binding domain, three Follistatin domains that contain EGF-like and kazal-like motifs, and a highly acidic C-terminal tail. Follistatin is a secreted protein that binds to ligands of the TGF-Beta family and regulates their activity by inhibiting their access to signaling receptors. It was originally discovered as activin antagonists whose activity suppresses expression and secretion of the pituitary hormone FSH (follicle stimulating hormone). In addition to being a natural antagonist, follistatin can inhibit the activity of other TGF-Beta ligands including BMP-2,-4,-6,-7, Myostatin, GDF-11, and TGF-Beta1. Follistatin is expressed in the pituitary, ovaries, decidual cells of the endometrium, and in some other tissues. Recombinant human Follistatin is a 37.8 kDa protein containing 344 amino acids.

According to scientific study based on animal test subjects, the primary function of Follistatin 344 is to bind and bioneutralize members of the TGF-β superfamily; a large group of structurally related cell regulatory proteins. The peptide has been shown to have a particular focus on activin, a protein complex that works to enhance follicle stimulating hormone biosynthesis and secretion. Studies have indicated that Follistatin 344 binds directly to activin and works specifically as an activin antagonist to inhibit the biosynthesis and secretion of follicle-stimulating hormone (FSH)

The roots of Follistatin 344’s overall functionality can be traced back to the solliculostellate (FS) cells of the anterior pituitary gland. This is the pea-sized gland that is located at the bottom of the hypothalamus at the base of the brain and is chiefly responsible for the control and regulation of several endocrine-related operations in an animal test subject’s body.

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6. Seller's Information:

Company: Shanghai Yijing Pharmaceutical Co., Ltd
Mob: +OO86-13O26163653

7. How to place an order:

Send me an email at the address above, tell me product name and quantity.

  CAS Registry Number:

00-00-0


  Company: Shanghai Yijing Pharmaceutical Co., Ltd     [ China ]        
  Contact: AlisaFollistatin 334Follistatin 334Follistatin 334
  Tel: +86-130-26163653
  Fax:
  Email: alisa@pharm-china.com
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