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Formestane CAS:566-48-3

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  Post Date: Aug 31,2016
  Expiry Date: Feb 27,2017
  Detailed Description: Cas No. :566-48-3 Quantity: 0.01Kilograms
Price:1.25 USD Kilograms
Formestane CAS:566-48-3
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Introduction:
Product Name: Formestane
Synonyms: Lentaron
CAS: 566-48-3
MF: C19H26O3
MW: 302.41
mp: 199-202°C
storage temp: 2-8°C
form: solid
Density: 1.19g/cm3
Melting Point: 199-202° C
Boiling Point: 475.4° Cat760mmHg
Refractive Index: 1.545
Flash Point: 255.4° C


Description:
Formestane (Lentaron) is a type I, steroidal aromatase inhibitor. It is used in the treatment of estrogen-receptor positive breast cancer in post-menopausal women. It is available as an intramuscular depot injection.

Formestane is often used to suppress estrogen production from anabolic steroids or prohormones. It also acts as a prohormone to 4-hydroxytestosterone, an active steroid which displays weak androgenic activity in addition to acting as a mild aromatase inhibitor.

Formestane has poor oral bioavailability and as such is no longer popular as many orally active aromatase inhibitors have been identified.

  CAS Registry Number:

566-48-3
  Synonyms: ;Formestane;B, Aromatase inhibitor;4-hydroxyandrost-4-ene-3,17-dione;(8xi,9xi,14xi)-4-methylandrost-4-ene-3,17-dione;4-Hydroxyandrostenedione;4-Hydroxy-4-androstenedione;
  Molecular Formula: C20H28O2
  Molecular Weight: 300.4351
  Molecular Structure: 566-48-3 4-androsten-4-ol-3,17-dione
  Hazard Symbols:  T:Toxic;
  Risk Codes: R60:;
  Safety Description: S53:;
S36/37/39:;
S45:;

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