Genz-123346
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Post Date: | Apr 03,2015 |
Expiry Date: | Apr 02,2016 |
Detailed Description: |
Cas No. :491833-30-8
Quantity: 50g Specs:98% purity Payment Method: T/T, Western Union Genz-123346 is a glucosylceramide synthase inhibitor with potential anticancer activity. Exposure of cells to Genz-123346 and to other GCS inhibitors at non-toxic concentrations can enhance the killing of tumor cells by cytotoxic anti-cancer agents. Genz-123346 and a few other GCS inhibitors are substrates for multi-drug resistance efflux pumps such as P-gp (ABCB1, gP-170). In cell lines selected to over-express P-gp or which endogenously express P-gp, chemosensitization by Genz-123346 was primarily due to the effects on P-gp function. |
CAS Registry Number: | 491833-30-8 |
Company: | Shanghai Sun-shineChemical Technology Co.,Ltd. [ China ] |
Contact: | Rosie |
Tel: | +86-027-59253327 |
Fax: | 0086-27-5925 3326 |
Email: | sales02@sun-shinechem.com |
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