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High-Quality Powder Somatomedin 1 Polypeptides (CAS: 667763-96-6)

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  Post Date: Aug 08,2017
  Expiry Date: Feb 04,2018
  Detailed Description: Cas No. :667763-96-6 Quantity: 500Kilograms
Price:2000 USD Kilograms
Somatomedin 1 belongs to the family of signaling molecules that play critical roles in cellular energy metabolism and in growth and development, especially prenatal growth . Also known as somatomedin C, is secreted from the liver into circulation in a process regulated by pituitary growth hormone (GH) and so it mediates the growth-promoting activity of GH. In the developing embryo Somatomedin 1 is expressed primarily by mesenchymal-derived cells. After birth Somatomedin 1 expression in most extrahepatic tissues declines and hepatic expression of it becomes GH-regulated. Expression of IGF-I outside the liver is regulated differently, depending on the specific tissues. For example, gonadotropins and sex steroids regulate Somatomedin 1 expression within the reproductive system, while parathyroid hormone and sex steroids regulate lgf-1 expression in bone. It is produced in several human tumors. It is mitogenic for a variety of cells including fibroblasts, osteoblasts, smooth muscle cells, fetal brain cells, neuroglial cells, and erythroid progenitor cells. lgf-1 exerts its actions exclusively through the Somatomedin 1 receptor . it induces endothelial cell migration and is involved in the regulation of angiogenesis.Email : anabolic@sinosteroids.com

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  CAS Registry Number:

667763-96-6


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