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High purity anti estrogen steroid Letrozole for anti cancer

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  Post Date: Feb 05,2017
  Expiry Date: Feb 05,2018
  Detailed Description: Cas No. :112809-51-5 Letrozole

EMAIL: cgf at chembj dot com
Whatsapp: +8615564141272

CAS NO: 112809-51-5
Molecular formula: C17H11N5
Molemular weight: 285.3
Purity: 99%
State: solid
Apperance: White Powder
Suitable for: adult
Certificaton: GMP, HSE, ISO 9001, USP
Standard: Enterprise standard
Usage: Used as API in Treatment of breast disease.

Description:

Femara is a new drug developed for the treatment of advanced breast cancer in women. Femara is the second in a new class of third-generation selective oral aromatase inhibitors.

It acts by blocking the enzyme aromatase, subsequently blocking the production of estrogen. Since many forms of breast cancer cells are stimulated by estrogen, it is hoped that by reducing amounts of estrogen in the body the progression of such a disease can be halted. This is the basic premise behind Nol vadex, except this drug blocks the action and not production of estrogen.

The effects of Femara can be quite dramatic to say the least. A daily dose of one tablet (2.5 mg) can produce estrogen suppression greater than 80 % in treated patients. With the powerful effect this drug has on hormone levels, it is only to be used (clinically) by post-menopausal women whose disease has progressed following treatment with Nolvadex. Side effects like hot flushes and hair thinning can be present, and would no doubt be much more severe in pre-menopausal patients.

  CAS Registry Number:

112809-51-5

  Synonyms: ;4,4'-(1h-1,2,4-Triazol-1-Ylmethylene)Bisbenzonitrile;Lelrozol;4,4'-(1h-1,2,4-Triazol-1-Ylmethylene) Bis-Benzonitrile;Femara;Letrozol;Letrazole;
  Molecular Formula: C17H11N5
  Molecular Weight: 285.31
  Molecular Structure: 112809-51-5 Letrozole

  Company: Jinan Jia Ge Biological Technology Co, Ltd     [ China ]        
  Contact: Lillian
  Tel: +86-15564141272
  Fax:
  Email: cgf@ycgmp.com
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