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Hot Sale Raw Powder Tauroursodeoxycholate With Competitive Price
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| Post Date: | Dec 28,2016 |
| Expiry Date: | Jun 26,2017 |
| Detailed Description: |
Cas No. :14605-22-2
Quantity: 1Metric Tons Price:1 USD Kilograms Payment Method: Wertern Union, Money Gram, T/T , Bitcoin Basic Info: Name:Tauroursodeoxycholate Apearance:Powdery CAS:14605-22-2 MF:C26H45NO6S MW:499.7 Shipment:EMS,DHL,UPS,Fedx Package:disguised Payment: Bank Transfer,Bitcoin,WU,MoneyGram Tauroursodeoxycholate Made-in-china Apearance:White Powder CAS:14605-22-2 MF:C26H45NO6S MW:499.7 Package:1kg/Foil bag S-adenosyl-L-methionine (SAMe) and tauroursodeoxycholate (TUDC) exert an additive ameliorating effect on taurolithocholate (TLC)-induced cholestasis. The aims were to investigate the protective effect of SAMe on 17beta-estradiol-glucuronide (17betaEG) cholestasis and to find out whether SAMe and TUDC may exert an additive, ameliorating effect. Hepatocyte couplet function was assessed by canalicular vacuolar accumulation (cVA) of cholyllysylfluorescein (CLF). Cells were co-treated with 17betaEG and SAMe, TUDC, or both (protection study), or treated with 17betaEG and then with SAMe, TUDC or both (reversion study) before CLF uptake. Couplets were also co-treated with SAMe and dehydroepiandrosterone (DHEA), a competitive substrate for the sulfotransferase involved in 17betaEG detoxification. The effects of 17betaEG, SAMe and TUDC were also examined on intracellular distribution of F-actin. Both SAMe and TUDC significantly protected against, and reversed, 17betaEG-induced cholestasis, but their effects were not additive. DHEA abolished the protective effect of SAMe. 17BetaEG did not affect the uptake of CLF into hepatocytes at the concentrations used, and also, it did not affect the intracellular distribution of F-actin. 17BetaEG does not affect the uptake of CLF into hepatocytes. SAMe and TUDC protect and reverse 17betaEG-induced cholestasis, but without an additive effect. Protection by SAMe may involve facilitating the sulfation of 17betaEG. Tag: top quality steroids powder factory; china pre-mixed liquids supplier Our advantages: 1. Highest quality, 98% min assay. 2. Reasonabel price. 2. Discreetly shipping. 3. Enough stock ensure the prompt delivery time. 4. Good after-sales service. 5. Discount for big order. 6. Resend policy. Any question, pls contact me: ychz04@chembj.com Company website: www.chinasteroids.com China top quality steroids powder factory and pre-mixed liquids supplier |
| CAS Registry Number: | 14605-22-2 |
| Synonyms: | ;9,10-secocholesta-5,7,10-trien-3-ol;2-{[(3alpha,5beta,7beta,8xi,9xi,14xi)-3,7-dihydroxy-24-oxocholan-24-yl]amino}ethanesulfonic acid;2-{[(3alpha,5beta,7beta)-3,7-dihydroxy-24-oxocholan-24-yl]amino}ethanesulfonic acid; |
| Molecular Formula: | C26H45NO6S |
| Molecular Weight: | 499.7036 |
| Molecular Structure: | 
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| Company: | China Anabolic Steroids Lab [ China ] |
| Contact: | Katharine Huang |
| Tel: | +86-731-22290202 |
| Fax: | +86-731-22290202 |
| Email: | bulksteroid@chembj.com |
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