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Hyaluronic acid sodium salt

Inquiry
  Post Date: Oct 16,2014
  Expiry Date: Apr 14,2015
  Detailed Description: Cas No. :9067-32-7

1.Discovery of HA:In 1934, Karl Meyer isolated a formerly unknown glycosaminoglycan from the vitreous humor of the bovine eye. It differed from any of the other previously discovered glycosamlnoglycans in that it did not contain sulffur. With its distinctive structure, its function within the body was unique. It was named hyaluronan and further scientific study ensued. At the time of its discovery, the new compound took on two names: hyaluronan when referring to its endogenous synthesis and hyaluronic acid when discussing research conducted outside of the body-huma or animal. Today hyaluronan is comonly referred to as hyaluronic acid, regardless of the context in which it is spoken.
2.Structure of HA:Hyaluronic Acid is linear, unbranched, high molecular weight polysaccharides containing a repeating disaccharide unit (D-glucuronic acid and N-acetyl glucosamine). HA, in its natural state, weighs about from 0.5-3.0 million daltons. Its weight lends itself to high viscosity and excellent lubrication within the body. The other glycosaminoglcans in the body include chondroitin sulfate, keratan sulfate, dermatan sulfate, and heparin sulfate.
3. Distribution of HA:HA widely consists in the extracelluar spaces of animal tissue. Almost kinds of animal tissue contain the different quantity of HA. Today Hyaluronic Acid has been found from skin, cockcomb, brain, vitreum, connective tissue, umbilical cord, human serum, articular fluid, gristle, human urine, cock embryo, oocyte, artery and vein etc.

Structural Formula:

HYALURONIC ACID(Topical Grade)

Items
Specifications
Description
White powder
pH
6.0~7.5
Glucuronic Acid
≥43%
Molecular Weight
≥1.00?á106
Transparency(in 0.1%aq.sol.,)
≥99.0%
Protein
≤0.1%
Loss on Drying
≤10.0%
Heavy Metals(Pb)
≤20ppm
Arsenic
≤2ppm
Nitrogen
3.0~4.0%
Kinematic Viscosity
≥40mm2/s
Bacteria Count
<10cfu/g
Mold and Yeast
<10cfu/g
Staphylococcus Aureus
Negative
Pseudomonas Aeruginosa
Negative

Usage Scope:cosmetic,ointment for external application etc.
Package:100g/bottle 1kg/bag


1%HYALURONIC ACID Solution(Topical Grade)

Items
Specifications
Description
Transparent,colorless
pH
6.0~7.5
Glucuronic Acid
≥4.8mg/ml
HYALURONIC ACID
≥1.0g/100ml
Transparency
≥99.0%
Protein
≤0.001%
Heavy Metals(Pb)
≤0.2|ìg/ml
Arsenic
≤0.02|ìg/ml
Intrinsic Viscosity
10000~18000mPa?¤s
Bacteria Count
<10cfu/g
Mold and Yeast
<10cfu/g
Staphylococcus Aureus
Negative

Usage Scope:cosmetic,ointment for external application etc.
Package:1kg/cask,25kg/cask or package by the request of customer


HYALURONIC ACID(Food Grade)

Items
Specifications
Description
White powder
pH
6.0~7.5
Glucuronic Acid
≥43%
Stake density
0.2~0.4g/cm3
Los on Drying
≤8.0%
Heavy Metals(Pb)
≤20ppm
Arsenic
Measure up to Chinese Pharmacopeia
Powerful Heat Remain
≤13.0%
Bacteria Count
<10cfu/g
Mold and Yeast
<10cfu/g
Staphylococcus Aureus
Negative
Salmonella
Negative
Escherichia Coli
Negative

Usage Scope:Nature health-care food for hairdressing and anti-caducity etc.
Package:100g/bottle 1kg/bag

  CAS Registry Number:

9067-32-7

  Synonyms: ;Hyaluronic acid sodium salt;HA Sodium;Hyaluronate Sodium;
  Molecular Formula: C28H44N2O23·Na
  Molecular Weight: 799.6366
  Molecular Structure: 9067-32-7 Sodium Hyaluronate
  Safety Description: S22:;
S24/25:;

  Company: Nova Biotech Shandong Co., Ltd.     [ China ]        
  Contact:
  Tel: +86-531-88875246/48/49
  Fax: +86-531-88875247
  Email: nova@nova-bt.com
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