L-Epinephrine hydrochloride
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| Post Date: | Jan 09,2018 |
| Expiry Date: | Jul 08,2018 |
| Detailed Description: |
Cas No. :329-63-5
Quantity: mass in stockKilograms Specs:white powder Price:negotiable USD Kilograms Payment Method: T/T, Western Union,Moneygram and Bitcoin. Description: Adrenaline hydrochloride is a vasoactive drug of anti shock, for the rescue of cardiac arrest and allergic shock, can also be used for other allergic diseases (such as asthma, urticaria) treatment. Combined with local anesthetics favorable local hemostasis and prolong the effect of medicine. L-Epinephrine hydrochloride is the active sympathomimetic hormone from the ADRENAL MEDULLA. It stimulates both the alpha- and beta- adrenergic systems, causes systemic VASOCONSTRICTION and gastrointestinal relaxation, stimulates the HEART, and dilates BRONCHI and cerebral vessels. It is used in ASTHMA and CARDIAC FAILURE and to delay absorption of local ANESTHETICS. Epinephrine Hydrochloride is the hydrochloride salt of the naturally occurring sympathomimetic amine with vasoconstricting, intraocular pressure-reducing, and bronchodilating activities. By stimulating vascular alpha-adrenergic receptors, epinephrine causes vasoconstriction, thereby increasing vascular resistance and blood pressure. When administered in the conjunctiva, this agent binds to alpha-adrenergic receptors in the iris sphincter muscle, resulting in vasoconstriction, a decrease in the production of aqueous humor, and a lowering of intraocular pressure. Through its beta1 receptor-stimulating actions, epinephrine increases the force and rate of myocardial contraction and relaxes bronchial smooth muscle, resulting in bronchodilation Applications: As a first aid to restore cardiac function: commonly used in anaphylactic shock, drowning, infectious diseases, drug poisoning, surgical accidents and cardiac conduction block caused by weak or sudden cardiac arrest. Heartbeat completely stopped, can be used intracardiac injection, and with effective artificial respiration, cardiac massage and other measures. For allergic diseases: subcutaneous or intramuscular injection can treat allergic diseases such as anaphylactic shock, urticaria, bronchial asthma, lobular inflammation, immune serum and vaccine-induced allergic reactions are also effective. Compatibility with local anesthetics Application: Per 100ml local anesthetic by adding 0.1% epinephrine solution 0.5 ~ 1ml, to shrink the local blood vessels, delay the absorption of local anesthetic, anesthesia time can be extended to reduce the toxicity of anesthetic reactions. Topical as a local hemostatic: local 1: 5000 ~ 1: 10 million solution, can make local vasoconstriction, stop nasal mucosa, uterus, gums or surgical site bleeding. Effects: The role of the heart L-Epinephrine can stimulate the heart of the β1 receptor, to enhance myocardial contractility, accelerate conduction, speed up the heart rate and increase cardiac output; can also dilate the coronary blood vessels, improve myocardial blood supply. Increased myocardial metabolism, can increase myocardial oxygen consumption, improve myocardial excitability. If the dose is too large or too fast intravenous injection can cause heart rate disorders, and even ventricular fibrillation. The role of blood vessels L-Epinephrine has a vasoconstrictive and diastolic effects, mainly due to the various parts of the blood vessels of different receptor types. This product on the α receptor-dominant skin, mucous membranes and visceral (such as the kidneys) of the blood vessels produce a strong contraction of the β2-receptor-dominant coronary and skeletal muscle vasodilatation. Elevated blood pressure When the heart excited, small doses can increase systolic blood pressure, diastolic blood pressure unchanged or decreased; large doses of systolic and diastolic blood pressure were increased. The role of smooth muscle Stimulate the bronchial smooth muscle β2 receptors, can quickly and powerful relaxation of bronchial smooth muscle, especially in the role of bronchial smooth muscle spasm more obvious; the gastrointestinal tract, bladder smooth muscle relaxation is weak, but its sphincter contraction. Dosage: Indications are mainly used for surgical epidural anesthesia.Adult for nerve block or infiltration anesthesia, a maximum dose of 150mg. Concentration of the preparation of the solution: surgical epidural block: 0.5% ~ 0.75% 10 ~ 20ml 50 ~ 150mg moderate to all motor block. |
| CAS Registry Number: | 329-63-5 |
| Synonyms: | (-)-3,4-dihydroxy-alpha-((methylamino)methyl)benzyl alcohol hydrochloride; (r)-4-(1-hydroxy-2-(methylamino)ethyl)-1,2-benzenediol hydrochloride; adrenalin chloride;Adrenaline Hydrochloride;Racepinephrine HCL;4-[1-hydroxy-2-(methylamino)ethyl]benzene-1,2-diol hydrochloride (1:1);Dl-Adrenaline Hydrochloride; |
| Molecular Formula: | C9H14Cl2NO3 |
| Molecular Weight: | 255.1189 |
| Molecular Structure: | 
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| Company: | Hengyang Desen Biotechnology Co., Ltd. [ China ] |
| Contact: | ava |
| Tel: | 86-18908446905 |
| Fax: | |
| Email: | ava@ycgmp.com |
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