Lanreotide
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| Post Date: | Sep 21,2016 |
| Expiry Date: | Sep 21,2017 |
| Detailed Description: |
Cas No. :118992-92-0;108736-35-2
Quantity: 1Kilograms Specs:alisa@pharm-china.com Price:1 USD Kilograms Payment Method: Western Union, MoneyGram, Bank transfer, Bite Lanreotide 1. Quick Details: Treating certain patients with acromegaly. It is also used to treat a certain type of cancer called neuroendocrine tumor from the gastrointestinal tract or the pancreas (GEP-NETs). It may also be used for other conditions as determined by your doctor. Lanreotide is a somatostatin analog. It works by reducing the levels of certain hormones (eg, growth hormone, insulin-like growth factor-1) in the blood. 2. We Guarantee: a. Fast Delivery: 3 work days after received payment. b. Free Resending: For long term cooperation, we guarantee all our customers will get their stuffs. c. Long Term Cooperation Discount: 5% DISCOUNT for our regular customers. 3. 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Your requirement 4. More Information About Lanreotide: The approval was based on demonstration of improved progression-free survival (PFS) in a multi-center, international, randomized (1:1), double-blind, placebo-controlled study (Trial 2- 55-52030-726) that enrolled 204 patients with unresectable, well- or moderately-differentiated, locally advanced or metastatic, non-functioning GEP-NETs. Fifty-five percent of patients (113/204) had neuroendocrine tumors arising outside the pancreas. Patients were randomized to receive either lanreotide 120 mg or placebo subcutaneously every 28 days. The primary efficacy endpoint was PFS as determined by independent radiology review. The trial demonstrated a significant prolongation of PFS for the lanreotide arm [HR 0.47 (95% CI: 0.30, 0.73); p < 0.001; log-rank test]. The median PFS in the lanreotide arm had not been reached at the time of the final analysis and will exceed 22 months. The median PFS in the placebo arm was 16.6 months. Safety data were evaluated in 101 patients who received at least one dose of lanreotide. The most commonly (greater than or equal to 10%) reported adverse reactions in lanreotide-treated patients were abdominal pain, musculoskeletal pain, vomiting, headache, injection site reaction, hyperglycemia, hypertension, and cholelithiasis. The most common serious adverse reaction of lanreotide observed in this trial was vomiting (4%). The recommended dose and schedule for lanreotide for GEP-NET is lanreotide 120 mg administered by deep subcutaneous injection every 28 days. Treatment should continue until disease progression or unacceptable toxicity. 5. 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| CAS Registry Number: | 118992-92-0;108736-35-2 |
| Synonyms: | ;B-naphthyl-D-ala-cys-tyr-D-trp*lys-val-cys-thr am;10-(4-aminobutyl)-N-(1-amino-3-hydroxy-1-oxobutan-2-yl)-16-(4-hydroxybenzyl)-13-(1H-indol-3-ylmethyl)-19-{[3-(naphthalen-2-yl)alanyl]amino}-6,9,12,15,18-pentaoxo-7-(propan-2-yl)-1,2-dithia-5,8,11,14,17-pentaazacycloicosane-4-carboxamide acetate (1:1);10-(4-aminobutyl)-N-(1-amino-3-hydroxy-1-oxobutan-2-yl)-16-(4-hydroxybenzyl)-13-(1H-indol-3-ylmethyl)-19-{[3-(naphthalen-2-yl)alanyl]amino}-6,9,12,15,18-pentaoxo-7-(propan-2-yl)-1,2-dithia-5,8,11,14,17-pentaazacycloicosane-4-carboxamide;Laromustine; |
| Molecular Formula: | C54H69N11O10S2 |
| Molecular Weight: | 1096.34 |
| Molecular Structure: | 
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| Company: | Shanghai Yijing Pharmaceutical Co., Ltd [ China ] |
| Contact: | Alisa |
| Tel: | +86-130-26163653 |
| Fax: | |
| Email: | alisa@pharm-china.com |
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