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Lansoprazole 103577-45-3

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  Post Date: Sep 15,2014
  Expiry Date: Sep 15,2015
  Detailed Description: Cas No. :103577-45-3 Quantity: 25Kilograms
Specs:assay 98%;packge 25kg/drum
Price:1 USD Metric Tons
Payment Method: Western Union, Bank Transter
Name Lansoprazole
Synonyms 2-[[3-Methyl-4-(2,2,2-trifluoroethoxy)pyridin-2-yl]methylsulfinyl]-1H-benzoimidazole
Lansoprazole Basic information
Product Name: Lansoprazole
Synonyms: 1h-benzimidazole,2-(((3-methyl-4-(2,2,2-trifluoroethoxy)-2-pyridinyl)methyl)su;2-(((3-methyl-4-(2,2,2-trifluoroethoxy)-2-pyridinyl)methyl)sulfinyl)-1h-benz;lfinyl)-;PREVACID;OGAST;LANSOPRAZOLE;LANSAPRAZOLE;LANSOX
CAS: 103577-45-3
MF: C16H14F3N3O2S
MW: 369.36
EINECS:
Product Categories: Active Pharmaceutical Ingredients;Intermediates & Fine Chemicals;Pharmaceuticals;Sulfur & Selenium Compounds;Ion Pump Inhibitors;Monovalent Ion Channels;Voltage-gated Ion Channels;ATPase;Pharmaceutical Intermediates;API Reference StandardFree Base API
Mol File: 103577-45-3.mol
Lansoprazole Chemical Properties
mp 178-182°C dec.
storage temp. 2-8°C
form powder
color off-white
CAS DataBase Reference 103577-45-3(CAS DataBase Reference)
Safety Information
Hazard Codes Xi
Risk Statements 36/37/38
Safety Statements 26-36
WGK Germany 2
RTECS DD9487500
Hazardous Substances Data 103577-45-3(Hazardous Substances Data)
MSDS Information
Provider Language
2-[[3-Methyl-4-(2,2,2-trifluoroethoxy)pyridin-2-yl]methylsulfinyl]-1H-benzoimidazole English
SigmaAldrich English
Lansoprazole Usage And Synthesis
Chemical Properties White Crystalline Powder
Usage Used as a gastric proton pump inhibitor. An antiulcerative
Usage anthelmintic
Biological Activity H + ,K + -ATPase inhibitor (IC 50 = 6.3 μ M) that displays antisecretory and antiulcer activity. Inhibits gastric acid secretion (IC 50 = 0.09 μ M for histamine-induced acid formation) and reduces gastric lesion formation induced by a variety of ulcerative stimuli. Antibacterial against Helicobacter pylori in vitro . Also blocks swelling-dependent chloride channel (ICIswell) in NIH3T3 fibroblasts. More potent than omeprazole (5-Methoxy-2-[[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfinyl]-1H-benzimidazole ).
Lansoprazole Preparation Products And Raw materials
Raw materials Acetic acid glacial-->Thionyl chloride-->Acetic anhydride-->tert-Butanol-->Vanadium pentoxide -->2,3-Lutidine-->2-Mercaptobenzimidazole

  CAS Registry Number:

103577-45-3
  Synonyms: ;2-{[[3-methyl-4-(2,2,2-trifluoroethoxy)2-pyridinyl]methyl]sulfonyl}1H-benzimidazole;2-({[3-methyl-4-(2,2,2-trifluoroethoxy)pyridin-2-yl]methyl}sulfinyl)-1H-benzimidazole;1-(1H-benzimidazol-2-yl)-2-[3-methyl-4-(2,2,2-trifluoroethoxy)-2-pyridyl]ethanone;lansoprazile;
  Molecular Formula: C17H14F3N3O2
  Molecular Weight: 349.3072
  Molecular Structure: 103577-45-3 lansoprazole
  Hazard Symbols:  Xi:Irritant;
  Risk Codes: R36/37/38:;
  Safety Description: S26:;
S36:;

  Company: Hubei MaxSource Chem Co., Ltd.     [ China ]        
  Contact: Tom Zhang
  Tel: +86-27-83555670
  Fax:
  Email: maxsource14@hotmail.com
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