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Levofloxacin hydrochloride CAS 100986-85-4 (jerryzhang001@chembj.com)

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  Post Date: Apr 20,2017
  Expiry Date: Apr 20,2018
  Detailed Description: Cas No. :100986-85-4 Payment Method: T/T; Western Union; Moneygram and Bitcoin
Levofloxacin hydrochloride CAS 100986-85-4


Product Name: Levofloxacin hydrochloride;
Synonyms: (s)-ofloxacin;7h-pyrido(1,2,3-de)-1,4-benzoxazine-6-carboxylicacid,2,3-dihydro-9-fluoro-3-m;dr3355;hemihydrate,(s)-ethyl-10-(4-methyl-1-piperazinyl)-7-oxo;LEVOFLOXACIN HCL;LEVOFLOXACIN HEMIHYDRATE;(3s)-9-fluoro-2,3-dihydro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-7h-pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylic acid monohydrochloride;Levofloxacin base;

CAS: 100986-85-4;
MF: C18H20FN3O4;
MW: 361.37;

Product Categories: Pharmaceutical material and intermeidates;Active Pharmaceutical Ingredients;Anti-Infective;Antibiotics for Research and Experimental Use;Biochemistry;Quinolones (Antibiotics for Research and Experimental Use);Peptide Synthesis/Antibiotics;Pharmaceutical intermediate;Antimicrobial;API;Pharmaceutical intermediates;Inhibitors;

Melting point: 218°C;
storage temp.: Store at 0-5°C;

HS Code: 29349990;

Description:

Levofloxacin, sold under the trade names Levaquin among others, is an antibiotic. It is used to treat a number of bacterial infections including acute bacterial sinusitis, pneumonia, urinary tract infections, chronic prostatitis, and some types of gastroenteritis. Along with other antibiotics it may be used to treat tuberculosis, meningitis, or pelvic inflammatory disease. It is available by mouth, intravenously, and in eye drop form.

Levofloxacin was approved for medical use in the United States in 1996.It is on the World Health Organization's List of Essential Medicines, the most effective and safe medicines needed in a health system. It is available as a generic medication. The wholesale cost in the developing world is about 0.44 to 0.95 USD per week of treatment.

Medical uses:

Levofloxacin is used to treat infections including: respiratory tract infections, cellulitis, urinary tract infections, prostatitis, anthrax, endocarditis, meningitis, pelvic inflammatory disease, traveler's diarrhea, tuberculosis, and plague and is available by mouth, intravenously, and in eye drop form.

Levofloxacin is used for the treatment of pneumonia, urinary tract infections, and abdominal infections. As of 2007 the Infectious Disease Society of America (IDSA);

Levofloxacin and other fluoroquinolones have also been widely used for the treatment of uncomplicated community-acquired respiratory and urinary tract infections, indications for which major medical societies generally recommend the use of older, narrower spectrum drugs to avoid fluoroquinolone resistance development. Due to its widespread use, common pathogens such as Escherichia coli and Klebsiella pneumoniae have developed resistance.

Pregnancy and breastfeeding:

According to the FDA approved prescribing information, levofloxacin is pregnancy category C.[8] This designation indicates that animal reproduction studies have shown adverse effects on the fetus and there are no adequate and well-controlled studies in humans, but the potential benefit to the mother may in some cases outweigh the risk to the fetus. Other fluoroquinolones have also been reported as being present in the mother's milk and are passed on to the nursing child

  CAS Registry Number:

100986-85-4
  Synonyms: ;(+-)-9-Fluoro-2,3-dihydro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-7H-pyrido(1,2,3-de)-1,4-benzoxazine-6-carboxylic acid;7H-Pyrido(1,2,3-de)-1,4-benzoxazine-6-carboxylic acid, 9-fluoro-2,3-dihydro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-, (+-)-;Floxin;Floxin Otic;Ofloxacin Otic;Ofloxacina;Ofloxacine;Ofloxacino;Ofloxacinum;Oxaldin;OFLX;(-)-Ofloxacin;(S)-(-)-Ofloxacin;(S)-9-Fluoro-2,3-dihydro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-7H-pyrido(1,2,3-de)-1,4-benzoxazine-6-carboxylic acid;(S)-Ofloxacin;Levaquin;Levofloxacino;Levofloxacinum;Ofloxacin S-(-)-form;Levofloxacin;(-)-(S)-9-Fluoro-2,3-dihydro-3-methyl-10-(4-methyl-1-piperazin-yl)-7-oxo-7H-pyrido(1,2,3-de)-1,4-benzoxazine-6-carboxylic acid;9-fluoro-3-methyl-10-(4-methylpiperazin-1-yl)-7-oxo-2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylic acid;(3S)-9-fluoro-3-methyl-10-(4-methylpiperazin-1-yl)-7-oxo-2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylic acid;
  Molecular Formula: C18H20O4N3F
  Molecular Weight: 361.3675
  Molecular Structure: 100986-85-4 ofloxacin
  Safety Description: S22:;
S24/25:;

  Company: Nanjing Bangnuo Biotechnology Co., Ltd.     [ China ]        
  Contact: Jerry Zhang
  Tel: 86-25-52198306
  Fax:
  Email: jerryzhang001@chembj.com
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