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Lincomycin Hcl

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  Post Date: Mar 06,2013
  Expiry Date: Sep 02,2013
  Detailed Description: Cas No. :859-18-7 Payment Method: T/T ,Western Union Moneygram and other
Synonyms: Lincomycin Hydrochloride

CAS: 859-18-7

EINECS 212-726-7

Assay: 82.5~95.5%

Standard: EP7.0/BP/USP

Packing: 20Bou/cardboard drum

MF: C18H35ClN2O6S

MW: 443

Character: White crystalline powder. MP 156-158°C, PH3.5~5.5, Optical rotation +135~+150°. Solubility: H2O: 50 mg/mL, clear, colorless.

Usage: An antibiotic produced by Streptomyces lincolnensis. Lincomycin is a lincosamide antibiotic that forms cross-links within the peptidyl transferase loop region of the 23S rRNA. Inhibits bacterial protein synthesis. Antibacterial.

Lincomycin (hereinafter referred to as LCM) biosynthesis, in addition to produce LCM, but under certain conditions, also produced the LCM B, C, D, K, S and other analogues, thus refining process more difficult and costly.

LD50 acute toxicity test showed that mice injected 1000mg/kg, rat oral greater than 4000mg/kg, toxicity is low.

Indications: Effect as erythromycin, do not have to do skin test, the product of Gram-positive bacteria and gram-negative bacteria is stronger for osteomyelitis, sepsis, respiratory and soft tissue infections. This product is very strong penetration of bone, is the medicine of choice for osteomyelitis.



  CAS Registry Number:

859-18-7

  Synonyms: ;Lincomycin Hcl;lincomycin hydrochloride;methyl 6,8-dideoxy-6-{[(4R)-1-methyl-4-propyl-L-prolyl]amino}-1-thio-D-erythro-alpha-D-galacto-octopyranoside hydrochloride;Lincomycin hydrochloride anhydrous;methyl 6,8-dideoxy-6-{[(4R)-1-methyl-4-propyl-L-prolyl]amino}-1-thio-D-erythro-alpha-D-galacto-octopyranoside hydrochloride (1:1);hydrogen chloride methyl 6,8-dideoxy-6-{[(4R)-1-methyl-4-propyl-L-prolyl]amino}-1-thio-D-erythro-alpha-D-gluco-octopyranoside (1:1:1);
  Molecular Formula: C18H35ClN2O6S
  Molecular Weight: 442.9983
  Molecular Structure: 859-18-7 Lincocin Hydrochloride
  Hazard Symbols:  Xi:Irritant;
  Risk Codes: R36/37/38:;
  Safety Description: S26:;

  Company: Shenzhen ShiJinGu Pharmaceutical Factory     [ China ]        
  Contact: Jessie Jiang
  Tel: 86-0755-61930361
  Fax: 86-0755-84556470
  Email: zc05@yccreate.com
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