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Losartan potassium

Inquiry
  Post Date: Jan 09,2018
  Expiry Date: Jul 08,2018
  Detailed Description: Cas No. :124750-99-8 Quantity: mass in stockKilograms
Specs:white powder
Price:negotiable USD Kilograms
Payment Method: T/T, Western Union,Moneygram and Bitcoin.
Description:

Losartan, sold under the trade name Cozaar among others, is a medication mainly used to treat high blood pressure.Other uses include for diabetic kidney disease, heart failure, and left ventricular enlargement. It is taken by mouth. It may be used together with other blood pressure medication. Up to six weeks may be required for the full effects to occur.

Common side effects include muscle cramps, stuffy nose, cough, and high blood potassium. Severe side effects may include angioedema, low blood pressure, and kidney problems. Use during pregnancy may result in harm to the baby. Use is not recommended during breastfeeding. It is in the angiotensin II receptor antagonist family of medication and works by blocking angiotensin II.

Medical uses
As with all angiotensin II type 1 receptor (AT1) antagonists, losartan is used to treatment hypertension. It may also delay progression of diabetic nephropathy and is associated with a positive clinical outcome in that regard. It is a suitable pharmacological agent for the reduction of renal disease progression in patients with type 2 diabetes, hypertension, and microalbuminuria (>30 mg/24 hours) or proteinuria (>900 mg/24 hours).

Although evidence shows calcium channel blockers and thiazide-type diuretics are preferred first-line treatments for most people (due to both efficacy[citation needed] and cost), an angiotensin II receptor antagonist such as losartan is recommended as first-line treatment in people under the age of 55 who cannot tolerate an ACE inhibitor. One study demonstrated losartan was superior to atenolol in the primary prevention of adverse cardiovascular events (myocardial infarction or stroke), with a reduction in cardiovascular morbidity and mortality for a comparable reduction in blood pressure. The maximal effects on blood pressure usually occur within 3–6 weeks of starting losartan.

  CAS Registry Number:

124750-99-8

  Synonyms: ;potassium 5-(4'-{[2-butyl-4-chloro-5-(hydroxymethyl)-1H-imidazol-1-yl]methyl}biphenyl-2-yl)tetrazol-1-ide;potassium (2-butyl-4-chloro-1-{[2'-(2H-tetrazol-5-yl)biphenyl-4-yl]methyl}-1H-imidazol-5-yl)methanolate;2-Butyl-4-chloro-1-[[2'-(1H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-1H-imidazole-5-methanol monopotassium salt;
  Molecular Formula: C22H22ClKN6O
  Molecular Weight: 461.001
  Molecular Structure: 124750-99-8 Losartan Potassium

  Company: Hengyang Desen Biotechnology Co., Ltd.     [ China ]        
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