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Lovastatin

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  Post Date: Nov 02,2024
  Expiry Date: May 01,2025
  Detailed Description: Cas No. :75330-75-5 Specs:USP
Quick Details:
Name: Lovastatin
CAS NO: 75330-75-5
MF: C24H36O5
MW: 404.55
Appearance: white powder
Standard:USP
Package:25kg/drum
Storage: shading, sealed.
Use: it is mainly used for the treatment of hypercholesterolemia and mixed hyperlipidemia

Description:
Lovastatin (Merck's Mevacor) is a statin drug, used for lowering cholesterol (hypolipidemic agent) in those with hypercholesterolemia to reduce risk of cardiovascular disease. Lovastatin is a naturally occurring compound found in food such as oyster mushrooms, red yeast rice,and Pu-erh.

Specification:

Test Items Standard Result
Description A white to off-white, crystalline powder Conforms
Identification IR/UV Conforms
Specific optical rotation +324°- +338° +326.8°
Loss on drying ≤0.3% 0.10%
Sulphated ash ≤0.2% 0.03%
Heavy metals ≤20ppm <20ppm
Related compound A ≤0.5% 0.24%
Assay(HPLC) 98.5%-101.0% 99.5%
HPLC
Purity RRT0.66 ≤0.15% 0.06%
RRT0.92 ≤0.15% 0.09%
RRT1.49 ≤0.15% 0.14%
RRT2.43 ≤0.15% 0.15%
Max unknown impurity ≤0.10% 0.08%
Total impurity ≤1.0% 0.66%
Residual solvents Ethanol ≤5000ppm 410ppm
Butyl Acetate ≤5000ppm 120ppm
Conclusion The results conform with USP35 standard

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1. Products protected by valid patents are not offered for sale in jurisdictions where the sale of such products constitutes a patent infringement. The current list only reflects the products and technologies that are available, under development: note that some products may be developed or produced for internal and experimental uses with no commercal aim.
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3. R&D use in accordance with (1) 35 USC 271(e)+A13(1) in the U.S.; (2) Section 69.1 of Japanese Patent Law in Japan; (3) Section 11, No. 2 of the German Patent Act of 1981 in Germany; (iv) Section 60, Paragraph 5b of the U.K. Patents Act of 1977 in the U.K.; (4) Sections 55.2(1) and 55.2(6) and other common law exemptions of Canadian patent law; (5) Section 68B of the Patents Act of 1953 in New Zealand together with the amendment of same by the Statutes Amendment Bill of 2002; (6) such related legislation and/or case law as may be or become applicable in the aforementioned countries; and (7) such similar laws and rules as may apply in various other countries.

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  CAS Registry Number:

75330-75-5

  Synonyms: ;mevlor;msd803;oxy)-1-naphthaleneheptanoicaciddelta-lactone ;Lovastation;Lovastin;Lovalip;Mevinolin;8-[2-(4-hydroxy-6-oxotetrahydro-2H-pyran-2-yl)ethyl]-3,7-dimethyl-1,2,3,7,8,8a-hexahydronaphthalen-1-yl 2-methylbutanoate;(1S,3R,7S,8S,8aR)-8-{2-[(2R,4R)-4-hydroxy-6-oxotetrahydro-2H-pyran-2-yl]ethyl}-3,7-dimethyl-1,2,3,7,8,8a-hexahydronaphthalen-1-yl (2S)-2-methylbutanoate;(1S,3R,7S,8S)-8-{2-[(2R,4R)-4-hydroxy-6-oxotetrahydro-2H-pyran-2-yl]ethyl}-3,7-dimethyl-1,2,3,7,8,8a-hexahydronaphthalen-1-yl (2S)-2-methylbutanoate;Red Yeast Rice P.E;
  Molecular Formula: C24H36O5
  Molecular Weight: 404.5396
  Molecular Structure: 75330-75-5 Lovastatin
  Safety Description: S22:;
S24/25:;

  Company: Taizhou Tianrui Chempharm Co., Ltd.     [ China ]          
  Contact:
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  Email: sales@tianruipharm.com
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