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Megestrol acetate

Inquiry
  Post Date: Sep 02,2015
  Expiry Date: Feb 29,2016
  Detailed Description: Cas No. :595-33-5 Product Details
Basic Info.
Model NO.:595-33-5
Product Name:Megestrol Acetate
CAS No.:595-33-5
Appearance:Crystalline Solid Powder
Export Markets:Global
Polciy:Re-Shipping Policy
Delivery:3-7 Working Days Door to Door
Additional Info.
Packing:1kg/Aluminum Foil Bag or as Your Requirement
Standard:SGS, ISO9001, KOSHER
Origin:China
HS Code:3001
Production Capacity:1500kg/Month
Product Description

1.  Quick Detail:
 
Megestrol acetate
Megestrol acetate Product Name:Megestrol acetate
Megestrol acetate CAS:595-33-5
Megestrol acetate MF:C24H32O4
MW:384.51
EINECS:209-864-5
mp:214°C
Megestrol acetate refractive index:11°(C=2, CHCl3)
Megestrol acetate Chemical Properties:Crystalline Solid
Megestrol acetate Usage:Progestogen;Progesterone receptor agonist,Orally active progestogen; formerly used in combinations as oral contraceptive,treatment of endometrial hyperplasia

2.  Description:


Megestrol acetate (INN, USAN, BAN, JAN) (abbreviated as MGA or MA, and sold mainly under the brand names Megace and Megace ES), also known as 17α-acetoxy-6-dehydro-6-methylprogesterone, is a steroidal progestin and progesteronederivative (specifically, a 17-hydroxylated progesterone) with predominantly progestational and antigonadotropiceffects.
Though sometimes referred to simply as megestrol, it is important to clarify that megestrol acetate is not the same asmegestrol, which is a closely related but different compound.

3.Application:

Megestrol acetate is used mainly as an appetite stimulant in a variety of conditions and as an antineoplastic agent in the treatment of breast, endometrial, and prostate cancers. When given in relatively high doses, it can substantially increase appetite in most individuals, even those with advanced cancer, and is often used to boost appetite and induceweight gain in patients with cancer or HIV/AIDS-associated cachexia. It is also used as a contraceptive in combination with an estrogen at relatively low doses.
In addition to its use in humans, megestrol acetate has been used extensively in veterinary medicine in the treatment of medical conditions in cats and dogs.

Megestrol acetate COA

Test Items  Specification  Test Results
Appearance White to creamy white crystalline powder White crystalline powder
Identification IR Complies
Completeness of solution Meets the requirements.500mg being  Complies
  dissolved in 10ml of acetone  
Solubility Insoluble in water, sparingly soluble in  Complies
  alcohol. Slightly soluble in ether and in   
  fixed oils, soluble in acetone; very soluble  
  in chloroform.  
Melting range 213ºC~220ºC  217ºC
Specific optical rotation +8.8°~ +12.0° +11.6°
Water ≤0.5% 0.1%
Residue roration ≤0.2% 0.06
Heavy metals ≤0.002% Complies
Assay 97.0%~103.0% 99.6%
Residual solvents Methanol≤1000ppm 74ppm
  Ethanol≤1000ppm 39ppm
  Methylene chloride≤500ppm 28ppm
  Tetrahydrofuran≤300ppm ND
  Benzene≤2ppm ND


  
  4.   Our advantange
 
Packing
 
 Professional packing with professional materials, and We'll give clients several Packing way to choose after you contact me through my email
 
Quality
 
 Our company is a professional leading factory in China in pharmaceutical area, ach batch of steroid powders have to tested by our QC(quality control) department before they are allowed to sell.
 
Delivery
 
 We can pack your powders within 48 hours after your payment, and corresponding picture of your powders' parcel will be sent to you.
 
Price
 
 Best prices you're sure to be satisfied, the more you buy, the more competitive prices you get.
 
Payment
 
T/T in advance , WU or Money Gram.


  CAS Registry Number:

595-33-5
  Synonyms: ;17-hydroxy-6-methylpregna-4,6-diene-3,20-dione 17-acetate;6-methyl-3,20-dioxopregna-4,6-dien-17-yl acetate;3,20-dioxopregna-4,6-dien-17-yl acetate;
  Molecular Formula: C23H30O4
  Molecular Weight: 370.4819
  Molecular Structure: 595-33-5 megestrol acetate
  Hazard Symbols:  Xn:Harmful;
  Risk Codes: R40:;
R48:;
  Safety Description: S22:;
S24/25:;

  Company: Hubei Yuancheng Saichuang Technology Co.,Ltd.     [ China ]        
  Contact: Silvia
  Tel: 027-50756101
  Fax: -
  Email: exo@yccreate.com
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