Misoprostol CAS:59122-46-2 cheryl@chembj.com
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| Post Date: | Dec 31,2015 |
| Expiry Date: | Dec 30,2016 |
| Detailed Description: |
Quantity: 3000Kilograms Specs:cheryl@chembj.com Price:1 USD Kilograms Payment Method: T/T , Moneygram , Westunion,Bitcoin High Purity Prohormones Steroids Misoprostol CAS:59122-46-2 for Terminate Pregnancy Misoprostol CAS:59122-46-2 Molecular Formula: C22H38O5 Molecular Weight: 382.60 Deleted CAS: 62015-39-8 Synonyms: Cytotec;Isprelor;Misogon;Misoprost;Misoprostil;SC29333 Boiling Point: 497.3 °C at 760 mmHg Flash Point: 160.3 °C Appearance: water-soluble, viscous liquid Solubility: Soluble to 100 mM in Ethanol Safety: Poison by ingestion, intramuscular, and intraperitoneal routes. When heated to decomposition it emits acrid smoke and irritating fumes. PackAge: Aluminium foil bag packing Storage: Keep in cool and dry place, away from light Use: Misoprostol is approved for use in the prevention of NSAID-induced gastric ulcers. It acts upon gastric parietal cells, inhibiting the secretion of gastric acid by G-protein coupled receptor-mediated inhibition of adenylate cyclase, which leads to decreased intracellular cyclic AMP levels and decreased proton pump activity at the apical surface of the parietal cell. Because other classes of drugs, especially H2-receptor antagonists and proton pump inhibitors, are more effective for the treatment of acute peptic ulcers, misoprostol is only indicated for use by people who are both taking NSAIDs and are at high risk for NSAID-induced ulcers, including the elderly and people with ulcer complications. Misoprostol is sometimes coprescribed with NSAIDs to prevent their common adverse effect of gastric ulceration (e.g. with diclofenac in Arthrotec). Misoprostol has other protective actions, but is only clinically effective at doses high enough to reduce gastric acid secretion. For instance, at lower doses, misoprostol may stimulate increased secretion of the protective mucus that lines the gastrointestinal tract and increase mucosal blood flow, thereby increasing mucosal integrity. However, these effects are not pronounced enough to warrant prescription of misoprostol at doses lower than those needed to achieve gastric acid suppression. However, even in the treatment of NSAID-induced ulcers, omeprazole proved to be at least as effective as misoprostol,but was significantly better tolerated, so misoprostol should not be considered a first-line treatment. Misoprostol-induced diarrhea and the need for multiple daily doses (typically four) are the main issues impairing compliance with therapy. |
| Company: | Hubei Yuancheng Saichuang Technology Co., Ltd [ China ] |
| Contact: | Cheryl |
| Tel: | 8618771024715 |
| Fax: | |
| Email: | cheryl@chembj.com |
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