| Detailed Description: |
Recombinantmouse MIP-1a is a single, non-glycosylated polypeptide chain containing 69amino acids and having a molecular weight of 7820 Da. The sequence of thefirst five N-terminal amino acids was determined to be Ala-Pro-Tyr-Gly-Ala.Contains less than 1%；This is an antibody fragment consisting of a single monomeric variable antibody domain directed to CCL3. Nanobody, with a molecular weight of only 12–15 kDa, is able to bind selectively to a specific antigen like a whole antibody.Chemokine (C-C motif) ligand 3 (CCL3) is aprotein that in humans is encoded by the CCL3 gene.CCL3, also known asMacrophage inflammatory protein-1α (MIP-1α), is a cytokine belonging to theCC chemokine family that is involved in the acute inflammatory state in therecruitment and activation of polymorphonuclear leukocytes (Wolpe et al.,1988). Sherry et al. (1988) demonstrated 2 protein components of MIP1, calledby them alpha and beta. http://www.creative-diagnostics.com/Recombinant-Mouse-Chemokine-C-C-motif-Ligand-3-a-a-69-Polypeptide-4209-427.htm
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