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N- acetyl -L- cysteine
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| Post Date: | Jun 11,2015 |
| Expiry Date: | Jun 10,2016 |
| Detailed Description: |
Cas No. :67-48-1
Quantity: 1Metric Tons Specs:1kg/ foil bag with discreet packgae Price:1 USD Kilograms Payment Method: T/T, WesterN Union, Money Gram N- acetyl -L- cysteine Chinese synonyms: N- acetyl -L-beta- cysteine; N- acetyl -L- cysteine; N- acetylcysteine; N- acetyl -L- cysteine; N- acetyl -L- cysteine sour; acetylcysteine; L- alpha acetyl amino beta mercaptopropionic acid; L- alpha acetyl amino beta mercaptopropionic acid English Name: N-Acetyl-cysteine English synonyms: (S) -ALPHA-AMINO-2-NAPHTHALENEPROPIONIC ACID RARECHEM BK PT 0097; N-ACETYL; CYSTEINE; N-ACETYL-3-MERCAPTOALANINE; N-ACETYL-L- (+) -CYSTEINE; N-ACETYL-L-CYSTEINE; N-ALPHA-ACETYL-L-CYSTEINE; 3- (2-NAPHTHYL) -ALANINE CAS number: 616-91-1 Molecular formula: C5H9NO3S Molecular weight: 163.19 EINECS number: 210-498-3 [description]: white crystals or crystalline powder [packing]: 25 kg / drum N- acetyl -L- cysteine can protect -1 alpha antitrypsin (elastase inhibitor) against hypochlorous acid (HOCl) and the effect of inactivation. Hypochlorous acid is a strong oxidizing agent activated phagocytic cells myeloperoxidase generated. These characteristics make this product particularly suitable for treatment with mucus and viscous secretions thick characterized by acute and chronic respiratory system infection. In addition, the molecular structure of the product to make it easy to penetrate the cell membrane. Within the cell, the product off acetyl L- cysteine, formation, which is a synthesis of glutathione (GSH) and the essential amino acid. GSH is a three peptide with high activity of a widely exists in various animal tissues. Glutathione is the most important protective agent in the cell integrity to maintain cell function and morphology of the cells is required. Oxygen free radicals and various cell toxin substances which can prevent cells from the receptor outside the damage. This product in maintaining proper GSH level plays an important role, so as to have cytotoxic damage helps protect cells from in vivo GSH level is too low and cause, such as acetaminophen poisoning cases. The mechanism of this effect is, in acetaminophen poisoning and in cyclophosphamide treated cases and in hemorrhagic cystitis, this product can also be used as a kind of special antidotes (in the latter case, this product provides the acrolein inactivation of essential thiol without the interference of chemical treatment, propylene formaldehyde is a toxic metabolite, an effect of urinary tract mucosa). Acute toxicity: the acute oral toxicity, intraperitoneal injection or intravenous acetylcysteine is low, in the normally fed rats and mice given a single oral administration of LD50 were >10g and >8g/kg, intravenous administration of rat 2.8g/kg, mouse 4.6g. Long term toxicity: after repeated dosing study, rats were orally administered 1g/kg/ a total of 12 weeks and 6 months, good tolerance. The dog was orally administered to 300mg/kg/ were a year, has not been found toxic reaction. Study on reproductive toxicity: Observation of rat and rabbit with large doses of N-acetylcysteine during pregnancy on offspring development period after organ no teratogenic effect. Study on mutagenicity: N-acetylcysteine had no mutagenesis (Ames test). Cancer research: toxicity test of N-acetylcysteine on animals and humans have shown no mutagenic effect, so not carcinogenic test. Food grade (also can be used in medicine) AJI-92 USP30 The content of 99% 108/kg |
| CAS Registry Number: | 67-48-1 |
| Synonyms: | ;2-Hydroxyethyl trimethylammonium chloride;Choline chloride, FCC Grade;2-hydroxy-N,N,N-trimethylethanaminium chloride;2-hydroxy-N,N,N-trimethylethanaminium chloride hydrochloride; |
| Molecular Formula: | C5H14ClNO |
| Molecular Weight: | 139.625 |
| Molecular Structure: | 
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| Hazard Symbols: |  Xi:Irritant; |
| Risk Codes: | R36/37/38:; |
| Safety Description: | S26:; S36:; |
| Company: | Zhuhai Shuangbojie Technology Co., Ltd [ China ] |
| Contact: | jeffyding |
| Tel: | +86-0765-8889897 |
| Fax: | +86-0765-8889806 |
| Email: | jeffyding@ycphar.com |
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