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NSI-189: A Nootropic Antidepressant That Promotes Neurogenesis

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  Post Date: Jun 08,2017
  Expiry Date: Jun 08,2018
  Detailed Description: Quantity: 50Kilograms
Specs:99% Purity
Price:1 USD Metric Tons
Payment Method: Western union,T/T,Money gram, Bitcoin
NSI-189: A Nootropic Antidepressant That Promotes Neurogenesis


Purported Benefits

As mentioned above, the potential benefits of NSI-189 are:

Improvement in behavioral responses associated with depression.[12]
Reversal of hippocampal atrophy.[13]
May enhance memory and cognition through increase neurogenesis, particularly in depressed subjects.
Positive effects may persist after treatment ceases

NSI-189 vs Other Antidepressants

What sets NSI-189 apart from other antidepressants already on the market (e.g., SSRIs)?

Like NSI-189, selective serotonin re-uptake inhibitors (SSRIs) also increase hippocampal neurogenesis. In fact, a famous paper published in Nature showed that SSRI-induced neurogenesis is required for the antidepressant effect. Hence, the fact that SSRIs increase serotonin in the synaptic cleft may be a kind of red herring; the "real" mechanism may in fact result from an increase in neuronal proliferation and integration of these nascent neurons into existing circuits.

Neuralstem identified NSI-189 using a novel approach (which is now patented). Instead of screening for drugs that increase synaptic serotonin or other monoamines, they directly screened a library of 10,000 compounds for their ability to increase neuronal proliferation, survival, and differentiation, leading to the discovery of NSI-189.


  Company: Wuhan Hengwo Scien-Tech Co., Ltd.     [ China ]        
  Contact: Kevin
  Tel: +86-15372431628
  Fax:
  Email: kevin@ycgmp.com
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