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Nifedipine

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  Post Date: Sep 10,2014
  Expiry Date: Mar 09,2015
  Detailed Description: Cas No. :21829-25-4 Quantity: 25Kilograms
Name Nifedipine
Synonyms Dimethyl 1,4-dihydro-2,6-dimethyl-4-(2'-nitrophenyl)-3,5-pyridinedicarboxylate; 1,4-Dihydro-2,6-dimethyl-4-(2-nitrophenyl)-3,5-pyridinedicarboxylic acid dimethyl ester
Product Name: Nifedipine
Synonyms: 1,4-dihydro-2,6-dimethyl-4-(2-nitrophenyl)-3,5-pyridinedicarboxylicaciddime;3,5-Pyridinedicarboxylic acid, 1,4-dihydro-2,6-dimethyl-4-(2-nitrophenyl)-, dimethyl ester;4-(2’-nitrophenyl)-2,6-dimethyl-1,4-dihydropyridin-3,5-dicarbonsaeuredimethy;5-pyridinedicarboxylicacid,1,4-dihydro-2,6-dimethyl-4-(2-nitrophenyl)-dim;Adalat CC;bay1040;corinfar;Dimethyl 1,4-dihydro-2,6-dimethyl-4-(o-nitrophenyl)-3,5-pyridinedicarboxylate
CAS: 21829-25-4
MF: C17H18N2O6
MW: 346.34
EINECS: 244-598-3
Product Categories: Pharmaceutical;Active Pharmaceutical Ingredients;Dihydropyridine Class Chemicals;Functional Materials;Photopolymerization Initiators;Intermediates & Fine Chemicals;Pharmaceuticals;Calcium channel;Ion Channels;Dihydropyridine;Pharmaceutical intermediate;Isotopically Labeled Pharmaceutical Reference Standard;CAPOTEN
Mol File: 21829-25-4.mol
Nifedipine Chemical Properties
mp 171-175 °C
storage temp. 2-8°C
solubility DMSO: soluble
form powder
color yellow
Water Solubility <0.1 g/100 mL at 19.5 ºC
Merck 6528
CAS DataBase Reference 21829-25-4(CAS DataBase Reference)
NIST Chemistry Reference Nifedipine(21829-25-4)
EPA Substance Registry System 3,5-Pyridinedicarboxylic acid, 1,4-dihydro-2,6-dimethyl-4-( 2-nitrophenyl)-, dimethyl ester(21829-25-4)
Safety Information
Hazard Codes Xn,Xi
Risk Statements 22-36/37/38
Safety Statements 26-36
WGK Germany 1
RTECS US7975000
HazardClass IRRITANT
MSDS Information
Provider Language
Nifedipine English
SigmaAldrich English
ACROS English
Nifedipine Usage And Synthesis
Chemical Properties Yellow Crystalline Solid
Usage Used as an antihypertensive and antianginal. A dihydorpyridine calcium channel blocker
General Description Odorless yellow crystals or powder. Tasteless.
Air & Water Reactions Aqueous solutions are very sensitive to light. . Insoluble in water.
Reactivity Profile Nifedipine is sensitive to light.
Fire Hazard Flash point data for Nifedipine are not available; however, Nifedipine is probably combustible.
Biological Activity L-type calcium channel blocker.
Nifedipine Preparation Products And Raw materials
Raw materials Ethyl cyanoacetate-->Diethyl oxalate-->Benzaldehyde-->2-Nitrotoluene-->Methyl acetoacetate-->2-Nitrobenzaldehyde-->4-Aminobenzaldehyde

  CAS Registry Number:

21829-25-4
  Synonyms: ;2,6-Dimethyl-3,5-dicarbomethoxy-4-(2-nitrophenyl)-1,4-dihydropyridine;2,6-diméthyl-4-(2-nitrophényl)-1,4-dihydropyridine-3,5-dicarboxylate de diméthyle;3,5-Pyridinedicarboxylic acid, 1,4-dihydro-2,6-dimethyl-4-(2-nitrophenyl)-, dimethyl ester;3,5-Pyridinedicarboxylic acid, 1,4-dihydro-2,6-dimethyl-4-(2-nitrophenyl)-, dimethyl ester (9CI);3,5-Pyridinedicarboxylic acid, 1,4-dihydro-2,6-dimethyl-4-(o-nitrophenyl)-, dimethyl ester (8CI);4-(2-Nitrophenyl)-2,6-dimethyl-3,5-dicarbomethoxy-1,4-dihydropyridine;Adalate;Adapress;Aldipin;Anifed;dimethyl 2,6-dimethyl-4-(2-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate;dimethyl (4S)-2,6-dimethyl-4-(2-nitrophenyl)-3,4-dihydropyridine-3,5-dicarboxylate;
  Molecular Formula: C17H18N2O6
  Molecular Weight: 346.3346
  Molecular Structure: 21829-25-4 Nifedipine
  Hazard Symbols:  Xn:Harmful;
  Risk Codes: R22:;
  Safety Description: S26:;
S36:;

  Company: Hubei MaxSource Chem Co., Ltd.     [ China ]        
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