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Omeprazole

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  Post Date: Feb 19,2013
  Expiry Date: Feb 19,2014
  Detailed Description: Cas No. :73590-58-6 Quantity: 10000Kilograms
Specs:White Crystalline Solid
Price:999 USD Metric Tons
Payment Method: tt
Omeprazole

CAS: 73590-58-6

Assay: 98.5% min. CP

Packing: 20Kg/cardboard drum

MF: C17H19N3O3S

MW: 345.42

Character: White Crystalline Solid. mp 156°C. solubility H2O: 0.5 mg/mL

Usage: Binds covalently to proton pump. It inhibits gastric secretion. Used as an anttiulcerative pharmaceutical raw materials.

Biological Activity: H + ,K + -ATPase inhibitor (IC 50 = 5.8 μ M) that displays antisecretory and antiulcer activity. Inhibits gastric acid secretion (IC 50 = 0.16 μ M for histamine-induced acid formation) and reduces gastric lesion formation induced by a variety of ulcerative stimuli. Antibacteral against Helicobacter pylori in vitro . Also inhibits CYP2C19, CYP2C9 and CYP3A (K i values are 3.1, 40.1 and 84.4 μ M respectively) and blocks swelling-dependent chloride channels (ICIswell).



  CAS Registry Number:

73590-58-6
  Synonyms: ;2-Chloromethyl-3,5-dinmethyl-4-methoxypyridine;5-Methoxy-2-[(4-methoxy-3,5-dimethyl-pyridin-2-yl)methylsulfinyl]-3H-benzoimidazole;ZOLTUM;R-(+)-OMEPRAZOLE;OMEPRAL;MOPRAL;MEPRAL;LOSEC;OMERPRAZOLE;
  Molecular Formula: C17H19N3O3S
  Molecular Weight: 345.42
  Molecular Structure: 73590-58-6 Omeprazole
  Hazard Symbols:  Xi:Irritant;
  Risk Codes: R36/37/38:;
  Safety Description: S26:;
S36:;

  Company: CENTRAL CHINA PHARMACEUTICAL FACTORY     [ China ]        
  Contact: SUNNY LOO
  Tel: +86-27-88325805
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  Email: gck16@yccreate.com
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