Omeprazole
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| Post Date: | Apr 17,2013 |
| Expiry Date: | Apr 17,2014 |
| Detailed Description: |
Cas No. :73590-58-6
Quantity: 20Metric Tons Assay: 98.5% min. CP Packing: 20Kg/cardboard drum MF: C17H19N3O3S MW: 345.42 Character: White Crystalline Solid. mp 156°C. solubility H2O: 0.5 mg/mL Usage: Binds covalently to proton pump. It inhibits gastric secretion. Used as an anttiulcerative pharmaceutical raw materials. Biological Activity: H + ,K + -ATPase inhibitor (IC 50 = 5.8 μ M) that displays antisecretory and antiulcer activity. Inhibits gastric acid secretion (IC 50 = 0.16 μ M for histamine-induced acid formation) and reduces gastric lesion formation induced by a variety of ulcerative stimuli. Antibacteral against Helicobacter pylori in vitro . Also inhibits CYP2C19, CYP2C9 and CYP3A (K i values are 3.1, 40.1 and 84.4 μ M respectively) and blocks swelling-dependent chloride channels (ICIswell). |
| CAS Registry Number: | 73590-58-6 |
| Synonyms: | ;2-Chloromethyl-3,5-dinmethyl-4-methoxypyridine;5-Methoxy-2-[(4-methoxy-3,5-dimethyl-pyridin-2-yl)methylsulfinyl]-3H-benzoimidazole;ZOLTUM;R-(+)-OMEPRAZOLE;OMEPRAL;MOPRAL;MEPRAL;LOSEC;OMERPRAZOLE; |
| Molecular Formula: | C17H19N3O3S |
| Molecular Weight: | 345.42 |
| Molecular Structure: | 
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| Hazard Symbols: |  Xi:Irritant; |
| Risk Codes: | R36/37/38:; |
| Safety Description: | S26:; S36:; |
| Company: | Shenzhen Shijingu Technology Co., Ltd [ China ] |
| Contact: | leihuizhou |
| Tel: | 86-755-89208994 |
| Fax: | 86-755-84556470 |
| Email: | sz10@yccreate.com |
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