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Paclitaxel

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  Post Date: Jun 25,2015
  Expiry Date: Jun 24,2016
  Detailed Description: Cas No. :33069-62-4 Paclitaxel
Synonyms: N-BENZYL-BETA-PHENYLISOSERINE ESTER;PACLITAXEL, TAXUS BREVIFOLIA;PACLITAXEL, TAXUS SPECIES;PACLITAXOL;PACLITAXEL;TAXOL(TM);taxol a;TAXOL EQUIVALENT
CAS: 33069-62-4
MF: C47H51NO14
MW: 853.91
EINECS: 205-285-7
Product Categories: Active Pharmaceutical Ingredients;Pharmaceutical material and intermeidates;Antineoplastics;Antineoplastic;APIs;Antitumors for Research and Experimental Use;Biochemistry;Natural Plant Extract;Intermediates & Fine Chemicals;Pharmaceuticals;Natural Anti-cancer Medical Materials and It's Derivatives;Antitumour;Signalling;Aromatics;Chiral Reagents;Heterocycles;Plant extract;API;Plant extracts;chemical reagent;pharmaceutical intermediate;phytochemical;reference standards from Chinese medicinal herbs (TCM).;standardized herbal extract;CLOBEX;Isolabel;antibiotic;Anti-cancer&immunity

mp 213 °C (dec.)(lit.)
refractive index -49 ° (C=1, MeOH)
storage temp. 2-8°C
solubility methanol: 50 mg/mL, clear, colorless
form powder
color white

Chemical Properties White Powder
Usage glucocorticoid, antiinflammatory
Usage An antineoplastic. Used in the study of structure and function of microtubles into tubulin. Paclitaxel is now used to treat patients with lung, ovarian, breast cancer, head and neck cancer, and advanc ed forms of Kaposi's sarcoma. Paclitaxel is a mitotic inhibitor used in cancer chemotherapy.
General Description Needles (from aqueous methanol) or fine white powder. An anti-cancer drug.
Air & Water Reactions May be sensitive to prolonged exposure to moisture. .
Health Hazard TOXIC; inhalation, ingestion or skin contact with material may cause severe injury or death. Contact with molten substance may cause severe burns to skin and eyes. Avoid any skin contact. Effects of contact or inhalation may be delayed. Fire may produce irritating, corrosive and/or toxic gases. Runoff from fire control or dilution water may be corrosive and/or toxic and cause pollution.
Fire Hazard Flash point data for Paclitaxel are not available. Paclitaxel is probably combustible.
Biological Activity Antitumor agent; promotes and stabilizes tubulin polymerization, causing cell cycle arrest. Induces autocatalytic activation of caspase-10 in CCRF-HSB-2 cells, triggering apoptosis.

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email adress : toni at ycgmp dot com
Tel:86-18872220727

  CAS Registry Number:

33069-62-4
  Synonyms: ;7,11-methano-5h-cyclodeca[3,4]benz[1,2-b]oxete benzenepropanoic acid deriv.;taxal;taxol a;Taxol;
  Molecular Formula: C47H51NO14
  Molecular Weight: 853.9061
  Molecular Structure: 33069-62-4 Paclitaxel
  Hazard Symbols:  Xn:Harmful;
  Risk Codes: R40:;
R41:;
  Safety Description: S26:;
S36/37/39:;
S45:;

  Company: Hulumimi Pharmaceuticals     [ China ]        
  Contact: Toni Zhong
  Tel: 86-18872220727
  Fax: 0086-27-88048077-794
  Email: toni@ycgmp.com
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