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Penfluridol
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| Post Date: | Feb 04,2015 |
| Expiry Date: | Feb 04,2016 |
| Detailed Description: |
Cas No. :26864-56-2
Product name: Penfluridol
CAS: 26864-56-2 Molecular formula: C28H27ClF5NO Molecular weight: 523.97 Description: Penfluridol (Semap, Micefal) is a highly potent, first generation diphenylbutylpiperidine antipsychotic. It was discovered at Janssen Pharmaceutica in 1968. Related to other diphenylbutylpiperidine antipsychotics, pimozide and fluspirilene, penfluridol has an extremely long elimination half-life and its effects last for many days after single oral dose. Its antipsychotic potency, in terms of dose needed to produce comparable effects, is similar to both haloperidol and pimozide. It is only slightly sedative, but often causes extrapyramidal side-effects, such as akathisia, dyskinesiae and pseudo-Parkinsonism. Penfluridol is indicated for antipsychotic treatment of chronic schizophrenia and similar psychotic disorders, it is, however, like most typical antipsychotics, being increasingly replaced by the atypical antipsychotics. Due to its extremely long lasting effects, it is often prescribed to be taken orally as tablets only once a week (q 7 days). The once-weekly doses is usually 10–60 mg. |
| CAS Registry Number: | 26864-56-2 |
| Synonyms: | ;1-(4,4-Bis(4-fluorophenyl)butyl)-4-hydroxy-4-(3-trifluoromethyl-4-chlorophenyl)piperidine;1-[4,4-Bis(4-fluorophenyl)butyl]-4-[4-chloro-3-(trifluoromethyl)phenyl]-4-piperidinol;1-[4,4-Bis(4-fluorophenyl)butyl]-4-[4-chloro-3-(trifluoromethyl)phenyl]piperidin-4-ol;1-[4,4-Bis(p-fluorophenyl)butyl]-4-(4-chloro-a,a,a-trifluoro-m-tolyl)-4-piperidinol;248-074-5;4-piperidinol, 1-[4,4-bis(4-fluorophenyl)butyl]-4-[4-chloro-3-(trifluoromethyl)phenyl]-;McN-JR 16341; |
| Molecular Formula: | C28H27ClF5NO |
| Molecular Weight: | 523.9651 |
| Molecular Structure: | 
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| Hazard Symbols: |  T:Toxic; |
| Risk Codes: | R25:; |
| Safety Description: | S45:; |
| Company: | AUSMAUCO BIOTECH CO., LIMITED [ China ] |
| Contact: | john |
| Tel: | +8618060810639 |
| Fax: | |
| Email: | plantsale@aus-bio.com |
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