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Pharmaceutical Glucocorticoid Anti Inflammatory , CAS 50-24-8 Prednisolone Allergies Steroids

Inquiry
  Post Date: Dec 30,2015
  Expiry Date: Dec 29,2016
  Detailed Description: Cas No. :50-24-8 Specs:Email:anthony@chembj.com
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Pharmaceutical Glucocorticoid Anti Inflammatory , CAS 50-24-8 Prednisolone Allergies Steroids

 

 

Product name

Prednisolone Factory Supplying

Other name

DEHYDROHYDROCORTISONE;HYDRODELTALONE;METACORT AND RALONE;METACORTANDROLONE

CAS register number

50-24-8

EINECS 

200-021-7

Molecular formula

C21H28O5

Molecular weight

360.44

Molecular structure

 Pharmaceutical Glucocorticoid Anti Inflammatory , CAS 50-24-8 Prednisolone Allergies Steroids

Melting point

240 °C

Assay

98%

 

  

Prednisolone is a steroid. It prevents the release of substances in the body that cause inflammation.Prednisolone is used to treat many different conditions such as allergic disorders, skin conditions, ulcerative colitis, arthritis, lupus, psoriasis, or breathing disorders. Prednisolone may also be used for purposes not listed in this medication guide.

Prednisolone is a synthetic adrenal corticosteroid. Corticosteroids are natural substances produced by the adrenal glands located adjacent to the kidneys. Corticosteroids have potent anti-inflammatory properties, and are used in a wide variety of inflammatory conditions such as arthritis, colitis, asthma, bronchitis, certain skin rashes, and allergic or inflammatory conditions of the nose and eyes. There are numerous preparations of corticosteroids including tablets, capsules, liquids, topical creams and gels, inhalers, eye drops, as well as injectable and intravenous solutions. The FDA approved prednisolone in June 1955

Prednisolone is used to achieve prompt suppression of inflammation in many inflammatory and allergic conditions. Examples of inflammatory conditions include rheumatoid arthritis, systemic lupus, acute gouty arthritis, psoriatic arthritis, ulcerative colitis, and Crohn's disease. Severe allergic conditions that fail conventional treatment may also respond to prednisolone. Examples include bronchial asthma, allergic rhinitis, drug-induced dermatitis, and contact and atopic dermatitis. Chronic skin conditions treated with prednisolone include dermatitis herpetiformis, pemphigus, severe psoriasis and severe seborrheic dermatitis. Chronic allergic and inflammatory conditions of the uvea, iris, conjunctiva and optic nerves of the eyes are also treated with prednisolone.

Prednisolone also is used in the treatment of blood cell cancers (leukemiias), and lymph gland cancers (lymphomas). Blood diseases involving destruction of platelets by the body's own immune cells (idiopathic thrombocytopenia purpura), and destruction of red blood cells by immune cells (autoimmune hemolytic anemia) can also be treated with prednisolone. Other miscellaneous conditions treated with prednisolone include thyroiditis and sarcoidosis. Prednisolone is also used as a hormone replacement in patients whose adrenal glands are unable to produce sufficient amounts of corticosteroids.

 

 

Product name

Prednisolone

Appearance

White crystalline powder

Chromatographic purity

Any individual impurity not more than 1.0%

Total impurities not more than 2.0%

0.5%

1.2%

Loss on drying

Not more than 0.5%

0.25%

Residue on ignition

Not more than 0.2%

0.06%

Residual solvents

Methanol≤3000ppm

Methylene Chloride≤600ppm

Chloroform≤60ppm

Tetrahydrofuran≤720ppm

400ppm

Not detect out

Not detect out

Not detect out

Assay

Between 97.0% and 102.0%

99.1%

Micronixation

90% not more than 10 microns

90% not more than 10

aicrons

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Guangzhou Quanao Chemical Co., Ltd. Is a collection research and development, production, marketing in an integrated modern large-scale chemical pharmaceutical enterprises.Is the national high and new technology enterprise, national biotechnology industrialization leading enterprise, national guard contract, heavy credit enterprise.Main business for the steroid drug substances and drug products development, production and sales.Main production covers an area of 433.49 acres, the existing staff more than 2300 people, including technical staff accounted for 15%, sales staff accounted for 35%, is a comprehensive drug substances and drug products manufacturers.


  CAS Registry Number:

50-24-8

  Synonyms: ;11-beta,17-alpha,21-trihydroxypregna-1,4-diene-3,20-dione;11,17,21-trihydroxypregna-1,4-diene-3,20-dione;(11beta)-11,17-dihydroxy-3,20-dioxopregna-1,4-dien-21-yl acetate;
  Molecular Formula: C23H30O6
  Molecular Weight: 402.4807
  Molecular Structure: 50-24-8 prednisolone
  Hazard Symbols:  Xn:Harmful;
  Risk Codes: R22:;

  Company: Guangzhou Quanao Chemical Co., Ltd     [ China ]        
  Contact: Anthony
  Tel: 18102817798
  Fax: 86-020-68886696
  Email: anthony@chembj.com
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