Praziquantel
Inquiry
| Post Date: | Jul 15,2015 |
| Expiry Date: | Jan 11,2016 |
| Detailed Description: |
Cas No. :55268-74-1
Quantity: 100Kilograms Price:671 RMB Kilograms Praziquantel English Name: Praziquantel CAS number: 55268-74-1 Molecular formula: C19H24N2O2 Molecular weight: 312.41 Content: 99% Packing: 25kg/ board barrel Quality standard: USP36 EINECS number: 259-559-6 Appearance: white or white crystalline powder, odorless, slightly bitter taste, hygroscopicity. Easy to be dissolved in two dimethyl sulfoxide. The melting point of 136 to 141 DEG C. Use of broad-spectrum anti parasitic drugs. For the treatment and prevention of schistosomiasis, cysticercosis, paragonimiasis, echinococcosis, Fasciolopsiasis, echinococcosis, worm infection. Use as a vermifuge, effective on animal gastrointestinal nematodes. Can mix in feed use. Use of the product is of Schistosoma japonicum, Schistosoma mansoni and S. haematobium, Clonorchis sinensis, paragonimiasis, Fasciolopsis and taeniasis and cysticercosis been effective anti worm medicine. Especially strong killing effect on schistosomiasis tapeworms, is currently the best a middle fruit. Use of anti worm medicine, mainly for schistosomiasis, also can be used for the Chinese branch of schistosomiasis, taeniasis and cysticercosis paragonimiasis, etc. Production method of industrial production and various synthetic routes: isoquinoline route, piperazine route and phenylethylamine route, which better with quinoline route. Catalytic hydrogenation by isoquinoline with benzoyl chloride and potassium cyanide addition, rearrangement of 1- benzoyl amino methyl -1, 2, 3, four 4- hydrogen isoquinoline, then by chloromethylation, cyclization, pressurized hydrolysis, cyclohexyl acylation and. Production method by using phenylethylamine as raw material, by acylation with chloroacetyl chloride, and then to two benzene carboxamide potassium amination reaction to introduce amino group, in three phosphorus oxychloride role under the condition 3, 4- two hydrogen isoquinoline derivatives, 1- aminomethyl four tetrahydroquinoline obtained by hydrogenation, hydrolysis, successively with cyclohexyl methyl chloride and chloroacetic chloride acylation, finally dehydrochlorination cyclizes to praziquantel. Can also be isoquinoline as raw materials, through Reissert reaction, at the L position and introduction of cyano nitrogen benzoylation, then hydrogenation, while benzoyl transfer to the side chain amino group, then in the ring on the amino introducing chloro acetyl, then cyclization, hydrolysis, cyclohexyl formylation to praziquantel. Price: 671/kg |
| CAS Registry Number: | 55268-74-1 |
| Synonyms: | ;Drontal;Drontal Plus;Vercom;2-(Cyclohexylcarbonyl)-1,2,3,6,7,11b-hexahydro-4H-pyrazino(2,1-a)isoquinolin-4-one;4H-Pyrazino(2,1-a)isoquinolin-4-one, 2-(cyclohexylcarbonyl)-1,2,3,6,7,11b-hexahydro-;5-24-03-00361 (Beilstein Handbook Reference);BRN 0761557;Biltricide;CCRIS 4114;Cutter Tape Tabs;Droncit;Embay 8440;Praziquantelum;Pyquiton;UNII-6490C9U457;4h-pyrazino(2,1-a)isoquinolin-4-one,2-(cyclohexylcarbonyl)-1,2,3,6,7,11b-hexah;Praziquentel;2-Cyclohexyl-carbonyl-1,3,4,6,7,11b-hexahydro-2H-pyrazine(2,1-a)isoquinoline-4-one; |
| Molecular Formula: | C19H24N2O2 |
| Molecular Weight: | 312.41 |
| Molecular Structure: | 
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| Company: | Hubei YuanCheng GongChuang Technology Co.Ltd [ China ] |
| Contact: | yangyuanyuan |
| Tel: | +86-027-68886696 |
| Fax: | +86-027-68886696 |
| Email: | wp3@chembj.com |
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