Home > Offer to Sell > Intermediates > Pharmaceutical intermediates > Progesterone

Progesterone

Inquiry
  Post Date: Apr 11,2016
  Expiry Date: Apr 11,2017
  Detailed Description: Cas No. :57-83-0 Progesterone

Pregnenolone
CAS NO.: 145-13-1

Assay: 99%

Molecular Formula:C21H32O2

Molecular Weight:316.48

Quality Standard: Enterprise Standard

Packing:1kg/foil bag

Appearance: White or almost white crystalline powder

Usage: Used as pharmaceutical intermediates progesterone
Manufacture:QuanAo
Delivery time:within 24 hours after payment
payment terms:WU, T/T, Bank Transfer,MoneyGram
Shipment: EMS, DHL, FeDex, etc


product details:

Pregnenolone (3β-hydroxypregn-5-en-20-one), also known as P5, is an endogenous steroid hormone. It is the precursor of the progestogens, mineralocorticoids, glucocorticoids, androgens, and estrogens, as well as the neuroactive steroids. In addition, pregnenolone is biologically active in its own right, acting as a neurosteroid.

Like other steroids, pregnenolone consists of four interconnected cyclic hydrocarbons. It contains ketone and hydroxyl functional groups, two methyl branches, and a double bond at C5, in the B cyclic hydrocarbon ring. Like many steroid hormones, it is hydrophobic. Its esterified version, pregnenolone sulfate, is water-soluble.

Pregnenolone undergoes further steroid metabolism in one of three ways.


Applications:

Pregnenolone can be converted to progesterone. The critical enzyme step is two-fold using a 3-beta-hydroxysteroid dehydrogenase and a delta 4-5 isomerase. The latter transfers the double bond from C5 to C4 on the A ring. Progesterone is the entry into the delta-4-pathway, resulting in production of 17-hydroxy progesterone and androstenedione, precursor to testosterone and estrone. Aldosterone and corticosteroids are also derived from progesterone or its derivatives.
Pregnenolone can be converted to 17-hydroxy-pregnenolone by the enzyme 17α-hydroxylase (CYP17A1). Using this pathway, termed delta-5 pathway, the next step is conversion to dehydroepiandrosterone using a desmolase. DHEA is the precursor of androstenedione.
Pregnenolone can be converted to androsta-5,16-dien-3 beta-ol by 16-ene synthetase

S k y p e:sales05_267
Email: sales05@ycphar.com
Tel:86-027-50756082
whatsApp:+8618872220733

  CAS Registry Number:

57-83-0

  Synonyms: ;3,20-pregnene-4;4-pregnene-3,20-dione;beta-progesterone;corlutin;corlutina;corluvite;corporin;corpus luteum hormone;delta4-pregnene-3,20-dione;delta(sup4)-pregnene-3,20-dione;flavolutan;fologenon;gestone;gestormone;glanducorpin;hormoflaveine;hormoluton;lipolutin;lucorteum sol;luteal hormone;luteinique;luteodyn;luteogan;luteohormone;luteol;luteosan;luteostab;luteovis;Lutex;lutidon;lutocyclin;lutocyclinm;lutocylin;lutocylol;lutoform;lutogyl;lutren;lutromone;piaponon;pranone;Pregn-4-ene-3,20-dione;pregnendione;pregnenedione;primolut;progekan;progesterol;progesteronum;progestin;progestone;prolidon;(S)-Pregn-4-en-3,20-dione;synovex s;syntolutan;(6alpha)-6-methyl-3,20-dioxopregn-4-en-17-yl acetate;Progesterone(micro) Progesterone;
  Molecular Formula: C21H30O2
  Molecular Weight: 314.468
  Molecular Structure: 57-83-0 Progesterone
  Hazard Symbols:  Xn:Harmful;
  Risk Codes: R40:;
  Safety Description: S36/37:;
S45:;

  Company: Hubei yuancheng Saichuang Tech, Ltd, Co     [ China ]        
  Contact: killy
  Tel: +86-027-50756082
  Fax:
  Email: sales05@ycphar.com
Disclaimer statement:The information and data included above have been realized by the enterprises and compiled by the staff, and are subject to change without notice to you. The Chemnet makes no warranties or representations whatsoever regarding the facticity, accuracy and validity of such information and data. In order to ensure your interest, we suggest you chose the products posted by our gold suppliers or VIP members.