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Prostaglandin F2a/Dinoprost

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  Post Date: Jan 09,2018
  Expiry Date: Jul 08,2018
  Detailed Description: Cas No. :551-11-1 Quantity: mass in stockKilograms
Specs:white powder
Price:negotiable USD Kilograms
Payment Method: T/T, Western Union,Moneygram and Bitcoin.
Prostaglandin F2α (PGF2α in prostanoid nomenclature), pharmaceutically termed dinoprost (INN), is a naturally occurring prostaglandin used in medicine to induce labor and as an abortifacient.

In domestic mammals, it is produced by the uterus when stimulated by oxytocin, in the event that there has been no implantation during the luteal phase. It acts on the corpus luteum to cause luteolysis, forming a corpus albicans and stopping the production of progesterone. Action of PGF2α is dependent on the number of receptors on the corpus luteum membrane.

The PGF2α isoform 8-iso-PGF2α was found in significantly increased amounts in patients with endometriosis, thus being a potential causative link in endometriosis-associated oxidative stress.

PGF2α acts by binding to the prostaglandin F2α receptor.In 2012 a concise and highly stereoselective total synthesis of PGF2α was described. The synthesis requires only seven steps, a huge improvement on the original 17-steps synthesis of Corey and Cheng, and uses 2,5-dimethoxytetrahydrofuran as a starting reagent, with S-proline as an asymmetric catalyst.

  CAS Registry Number:

551-11-1

  Synonyms: ;prostaglandin F2-alpha;Prostaglandin F2A;9,11,15-trihydroxyprosta-5,13-dien-1-oicacid;amoglandin;cyclosin;dinolytic;enzaprost;enzaprostf;glandin;9,11,15-trihydroxyprosta-5,13-dien-1-oic acid;(9alpha,11alpha,15S)-9,11,15-trihydroxyprosta-5,13-dien-1-oic acid;
  Molecular Formula: C20H34O5
  Molecular Weight: 354.481
  Molecular Structure: 551-11-1 dinoprost

  Company: Hengyang Desen Biotechnology Co., Ltd.     [ China ]        
  Contact: ava
  Tel: 86-18908446905
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