Home > Offer to Sell > Intermediates > Pharmaceutical intermediates > Raloxifene hydrochloride

Raloxifene hydrochloride

Inquiry
  Post Date: Feb 02,2016
  Expiry Date: Jul 31,2016
  Detailed Description: Cas No. :82640-04-8 Payment Method: money gram, western union, bank transfer, bit
Alias: RALOXIFENE HCL; ly156758; KEOXIFENE;KEOXIFENE HYDROCHLORIDE;LY 139481;AKOS 92138

Product Details:
Place of Origin: China
Certification: ISO9001
Brand:YuanCheng

Payment & Shipping Terms:

Minimum Order Quantity:1kg
Supply Ability:500kg/month
Delivery Time:within 24 hours after payment

Payment Terms:Western Union, MoneyGram, T/T
Package:25kg/cardboad drum
Appearance:light yellow

Product Description:
CAS: 82640-04-8
M.F.: C28H28ClNO4S
M.W. :510.04
Purity:99.8%
M.P.: 250-253°C
M.S.:



EVISTA (raloxifene hydrochloride) is an estrogen agonist/antagonist, commonly referred to as a selective estrogen receptor modulator (SERM) that belongs to the benzothiophene class of compounds

The chemical designation is methanone, [6-hydroxy-2-(4-hydroxyphenyl)benzo[b]thien-3-yl]-[4-[2-(1-piperidinyl)ethoxy]phenyl]-, hydrochloride. Raloxifene hydrochloride (HCl) has the empirical formula C28H27NO4S.HCl, which corresponds to a molecular weight of 510.05. Raloxifene HCl is an off-white to pale-yellow solid that is very slightly soluble in water.

EVISTA (raloxifene) is supplied in a tablet dosage form for oral administration. Each EVISTA tablet contains 60 mg of raloxifene HCl, which is the molar equivalent of 55.71 mg of free base. Inactive ingredients include anhydrous lactose, carnauba wax, crospovidone, FD&C Blue No. 2 aluminum lake, hypromellose, lactose monohydrate, magnesium stearate, modified pharmaceutical glaze, polyethylene glycol, polysorbate 80, povidone, propylene glycol, and titanium dioxide.


Usage:
Reduction in the incidence of invasive breast cancer in postmenopausal women with osteoporosis.
in 2006, the National Cancer Institute announced that raloxifene was as effective as tamoxifen in reducing the incidence of breast cancer in postmenopausal women at increased risk,

  CAS Registry Number:

82640-04-8

  Synonyms: ;Raloxifene hydrochloride [USAN];6-Hydroxy-2-(p-hydroxyphenyl)benzo(b)thien-3-yl-p-(2-piperidinoethoxy)phenyl ketone, hydrochloride;Evista;Keoxifene hydrochloride;LY 156758;Methanone, (6-hydroxy-2-(4-hydroxyphenyl)benzo(b)thien-3-yl)(4-(2-(1-piperidinyl)ethoxy)phenyl)-, hydrochloride;Raloxifene HCl;UNII-4F86W47BR6;[6-hydroxy-2-(4-hydroxyphenyl)-1-benzothiophen-3-yl]{4-[2-(piperidin-1-yl)ethoxy]phenyl}methanone hydrochloride (1:1);[6-hydroxy-2-(4-hydroxyphenyl)-2,3-dihydro-1-benzothiophen-3-yl][4-(2-piperidin-1-ylethoxy)phenyl]methanone;
  Molecular Formula: C28H29NO4S
  Molecular Weight: 475.5992
  Molecular Structure: 82640-04-8 Raloxifene hydrochloride

  Company: Zhuzhou Yuancheng Hezhong Technology Development     [ China ]        
  Contact: kathyyan
  Tel: 86-731-22292056
  Fax: 86-731-22292056
  Email: mxy044@yccreate.com
Disclaimer statement:The information and data included above have been realized by the enterprises and compiled by the staff, and are subject to change without notice to you. The Chemnet makes no warranties or representations whatsoever regarding the facticity, accuracy and validity of such information and data. In order to ensure your interest, we suggest you chose the products posted by our gold suppliers or VIP members.