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Raloxifene hydrochloride CAS 82640-04-8 Energy Improves

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  Post Date: Nov 25,2016
  Expiry Date: Nov 25,2017
  Detailed Description: Cas No. :82640-04-8 Raloxifene hydrochloride CAS 82640-04-8 Energy Improves

Raloxifene hydrochloride, CAS 82640-04-8

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Product Description:

Alias: RALOXIFENE HCL; ly156758; KEOXIFENE;KEOXIFENE HYDROCHLORIDE;LY 139481;AKOS 92138
CAS: 82640-04-8
M.F.: C28H28ClNO4S
M.W. :510.04
Purity:99.8%
M.P.: 250-253°C
Purity:98%min
Appearance: white crystalline powder
Packing:25kg/cardboard drum
Payment: Bank Transfer, Western Union, Money Gram
Express: EMS, DHL, FedEx, etc(door-to-door)


EVISTA (raloxifene hydrochloride) is an estrogen agonist/antagonist, commonly referred to as a selective estrogen receptor modulator (SERM) that belongs to the benzothiophene class of compounds

The chemical designation is methanone, [6-hydroxy-2-(4-hydroxyphenyl)benzo[b]thien-3-yl]-[4-[2-(1-piperidinyl)ethoxy]phenyl]-, hydrochloride. Raloxifene hydrochloride (HCl) has the empirical formula C28H27NO4S.HCl, which corresponds to a molecular weight of 510.05. Raloxifene HCl is an off-white to pale-yellow solid that is very slightly soluble in water.

EVISTA (raloxifene) is supplied in a tablet dosage form for oral administration. Each EVISTA tablet contains 60 mg of raloxifene HCl, which is the molar equivalent of 55.71 mg of free base. Inactive ingredients include anhydrous lactose, carnauba wax, crospovidone, FD&C Blue No. 2 aluminum lake, hypromellose, lactose monohydrate, magnesium stearate, modified pharmaceutical glaze, polyethylene glycol, polysorbate 80, povidone, propylene glycol, and titanium dioxide.


Usage:
Reduction in the incidence of invasive breast cancer in postmenopausal women with osteoporosis.
in 2006, the National Cancer Institute announced that raloxifene was as effective as tamoxifen in reducing the incidence of breast cancer in postmenopausal women at increased risk,

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  CAS Registry Number:

82640-04-8

  Synonyms: ;Raloxifene hydrochloride [USAN];6-Hydroxy-2-(p-hydroxyphenyl)benzo(b)thien-3-yl-p-(2-piperidinoethoxy)phenyl ketone, hydrochloride;Evista;Keoxifene hydrochloride;LY 156758;Methanone, (6-hydroxy-2-(4-hydroxyphenyl)benzo(b)thien-3-yl)(4-(2-(1-piperidinyl)ethoxy)phenyl)-, hydrochloride;Raloxifene HCl;UNII-4F86W47BR6;[6-hydroxy-2-(4-hydroxyphenyl)-1-benzothiophen-3-yl]{4-[2-(piperidin-1-yl)ethoxy]phenyl}methanone hydrochloride (1:1);[6-hydroxy-2-(4-hydroxyphenyl)-2,3-dihydro-1-benzothiophen-3-yl][4-(2-piperidin-1-ylethoxy)phenyl]methanone;
  Molecular Formula: C28H29NO4S
  Molecular Weight: 475.5992
  Molecular Structure: 82640-04-8 Raloxifene hydrochloride

  Company: Wuhan Yuancheng Gongchuang Technology Co., Ltd.     [ China ]        
  Contact: Sophia Zhang
  Tel: +86-027-50756082
  Fax:
  Email: sophia525@yccreate.com
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