Rivastigmine Tartrate
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| Post Date: | Sep 30,2017 |
| Expiry Date: | Sep 30,2018 |
| Detailed Description: |
Cas No. :129101-54-8
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. http://steroidraws.en.hisupplier.com/ , Rivastigmine Tartrate High Purity Nootropic Supplement Smart Drugs Rivastigmine Tartrate Quick Detail Product Name Rivastigmine Tartrate Rivastigmine Tartrate Alias Rivastigmine-d6 tartarate Rivastigmine Tartrate CAS 129101-54-8 Rivastigmine Tartrate MF C18H28N2O8 Rivastigmine Tartrate MW 400.4235 Rivastigmine Tartrate Purity 99% Rivastigmine Tartrate MP 123-125°C Rivastigmine Tartrate BP 316.2°C at 760 mmHg Rivastigmine Tartrate FP 145°C Grade Pharmaceutical Grade Appearance White Powder Rivastigmine Tartrate is a parasympathomimetic or cholinergic agent for the treatment of mild to moderate dementia of the Alzheimer's type and dementia due to Parkinson's disease. The drug can be administered orally or via a transdermal patch; the latter form reduces the prevalence of side effects, which typically include nausea and vomiting. Pharmacological Effects Rivastigmine Tartrate is rivastigmine Alzheimer's disease drugs, rivastigmine is physostigmine derivative by Novartis for the first time successfully developed the trade name Exelon (exelon), a molecule with there carbamate structure, is a kind of amino acid of selective cerebral cholinesterase inhibitor, can also inhibit the acetylcholinesterase and butyrylcholinesterase, cholinergic neurons by delaying the release of acetylcholine degradation and energy promoting cholinergic nerve conduction, can improve cognitive function disorders mediated by cholinergic, thereby improving the cognitive function of Alzheimer's disease patients. Rivastigmine Tartrate plasma protein binding is weak, easily through the blood-brain barrier, which has a high degree of brain selectivity. It not only selectively acts on the most easily affected cerebral cortex and hippocampus, but also preferentially inhibits the dominant subtype of AChE in the brain, resulting in a reduction in the efficacy of peripheral cholinergic side effects. Rivastigmine in vivo half-life is short and long duration of action. Unlike tacrine, this product in the hippocampus and cortex of G1 enzyme inhibitory effect is stronger. Clinic for the treatment of mild to moderate Alzheimer-type dementia, or Alzheimer's disease can be suspected Alzheimer's disease clinically. Rivastigmine Tartrate Dosage The dosage of Exelon to treat Alzheimer's Disease is 6-12 mg/day, given twice-a-day. The dose to treat Parkinson's Disease is 3-12 mg/day, given twice-a-day. Exelon may interact with atropine, belladonna, clidinium, dicyclomine, glycopyrrolate, hyoscyamine, mepenzolate, methantheline, methscopolamine, propantheline, or scopolamine. Tell your doctor all medications you are taking. During pregnancy, this medication should be used only when prescribed by a doctor. It is unknown if this medication passes into breast milk. Consult your doctor before breastfeeding. |
| CAS Registry Number: | 129101-54-8 |
| Synonyms: | ;SDZ-ENA 713;ENA 713;ENA-713;Rivastigmine hydrogentartrate;UNII-9IY2357JPE;Carbamic acid, ethylmethyl-, 3-((1S)-1-(dimethylamino)ethyl)phenyl ester, (2R,3R)-2,3-dihydroxybutanedioate (1:1);Carbamic acid, ethylmethyl-, 3-(1-(dimethylamino)ethyl)phenyl ester, (S)-, (R-(R*,R*))-2,3-dihydroxybutanedioate (1:1);Rivastigmine hydrogen tartrate;3-[(1S)-1-(dimethylamino)ethyl]phenyl ethyl(methyl)carbamate 2,3-dihydroxybutanedioate (1:1);3-[(1S)-1-(dimethylamino)ethyl]phenyl ethyl(methyl)carbamate 2,3-dihydroxybutanedioate (salt);Rivastigimine tartrate; |
| Molecular Formula: | C18H28N2O8 |
| Molecular Weight: | 400.4235 |
| Molecular Structure: | 
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| Company: | hubei gongchuang ltd.c [ China ] |
| Contact: | ulalee |
| Tel: | +86-571-15784251 |
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| Email: | gcgj11@ycphar.com |
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