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Salicylazosulfapyridine

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  Post Date: Jan 09,2018
  Expiry Date: Jul 08,2018
  Detailed Description: Cas No. :599-79-1 Quantity: mass in stockKilograms
Specs:white powder
Price:negotiable USD Kilograms
Payment Method: T/T, Western Union,Moneygram and Bitcoin.
Quick Details:

Product Name: Salicylazosulfapyridine
CAS NO: 599-79-1
Appearance: white powder
MF: C18H14N4O5S
Purity: 99%
Origin: China
Export market: Global
Grade: Pharmaceutical grade
Supply capacity: Mass in stock.
Usage: The intestinal sulphonamide


Packing: Well disguised package to pass the customs.
Payment: T/T, Western Union,Moneygram and Bitcoin.
Shiping: EMS,HKEMS,FEDEX,DHL,TNT,Aramex,etc
Leading time: Within 24 hours after payment.
Delivery time: 3-7 work days

99% passing rate & 100% free resend policy,


Description:

Sulfasalazine (SSZ), sold under the trade name Azulfidine among others, is a medication used to treat rheumatoid arthritis, ulcerative colitis, and Crohn's disease. It is often considered as a first line treatment in rheumatoid arthritis. It is taken by mouth.

Significant side effects occur in about 25% of people. Commonly these include loss of appetite, nausea, headache, and rash. Severe side effects include bone marrow suppression, liver problems, and kidney problems. It should not be used in people allergic to aspirin or sulfonamide. Use during pregnancy appears to be safe for the baby. Sulfasalazine is in the disease-modifying antirheumatic drugs (DMARDs) family of medications. It is unclear exactly how it works but is broken down into sulfapyridine and 5-aminosalicylic acid.

Sulfasalazine was approved for medical use in the United States in 1950. It is on the World Health Organization's List of Essential Medicines, the most effective and safe medicines needed in a health system. Sulfasalazine is available as a generic medication.

Medical uses
Sulfasalazine is used in the treatment of inflammatory bowel disease, including ulcerative colitis and Crohn's disease. It is also indicated for use in rheumatoid arthritis and used in other types of inflammatory arthritis (e.g. psoriatic arthritis and reactive arthritis).

It is usually not given to children under 2 years of age.

Side effects:
Sulfasalazine metabolizes to sulfapyridine. Serum levels should be monitored every three months, and more frequently at the outset. Serum levels above 50 μg/l are associated with side effects. In rare cases, Sulfasalazine can cause severe depression in young males. It can also cause temporary infertility. Immune thrombocytopenia has been reported.

Sulfasalazine inhibits dihydropteroate synthase, and can cause folate deficiency and megaloblastic anemia. and various other undesirable effects.

Sulfasalazine can cause hemolytic anemia in people with G6PD deficiency.

Sulfasalazine may cause stomach upset, nausea, vomiting, loss of appetite, headache, dizziness, or unusual tiredness. Skin and urine can become orange, with occasional allergic reactions.

  CAS Registry Number:

599-79-1

  Synonyms: ;salicylazosulfapyridine;2-hydroxy-5-[[4-[(2-pyridinylamino)sulfonyl]phenyl]azo]benzoic acid;5-(p-(2-pyridylsulfamoyl)phenylazo)salicylic acid;sulfasalazine;Sulphasalazine;(3Z)-6-oxo-3-{[4-(pyridin-2-ylsulfamoyl)phenyl]hydrazono}cyclohexa-1,4-diene-1-carboxylic acid;6-oxo-3-{[4-(pyridin-2-ylsulfamoyl)phenyl]hydrazono}cyclohexa-1,4-diene-1-carboxylic acid;2-hydroxy-5-{[4-(pyridin-2-ylsulfamoyl)phenyl]diazenyl}benzoic acid;2-hydroxy-5-{(E)-[4-(pyridin-2-ylsulfamoyl)phenyl]diazenyl}benzoic acid;
  Molecular Formula: C18H14N4O5S
  Molecular Weight: 398.3926
  Molecular Structure: 599-79-1 Salazosulfapyridine

  Company: Hengyang Desen Biotechnology Co., Ltd.     [ China ]        
  Contact: ava
  Tel: 86-18908446905
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