Sorafenib tosylate
Inquiry
| Post Date: | Jul 04,2016 |
| Expiry Date: | Jul 04,2017 |
| Detailed Description: |
Cas No. :475207-59-1
Chemical Name: 4 - {4 [3 - (4-chloro-3-trifluoromethyl-phenyl) ureide] phenoxy} pyridine-2-carboxamide p-toluenesulfonate Product Alias: toluenesulfonic sorafenib mesylate Sorafenib Sorafenib p-toluenesulfonic English name: Sorafenib tosylate English Synonyms: Sorafenib (Nexavar) CAS: 475207-59-1 Keywords: Sorafenib tosylate, sorafenib tosylate, mesylate Sorafenib, 475207-59-1 Molecular formula: C21H16ClF3N4O3.C7H8SO3 Molecular Weight: 637.03 Appearance: yellow or white crystalline powder Melting point: 225-235 ℃ Loss on drying: Less than 0.5% Heavy metals: Less than 10ppm Total impurities: less than 1.0% Content: 99% Packing: 1kg / aluminum foil bag Uses: toluenesulfonic Sorafenib is a novel multi-target anticancer drugs, can act simultaneously on tumor cells and tumor blood vessels. It has a dual anti-tumor effects: either by blocking the RAF / MEK / ERK-mediated cell signaling Pathway directly inhibit the proliferation of tumor cells, but also by inhibiting VEGF and platelet-derived Health growth factor (PDGF) receptors and block the formation of tumor angiogenesis, indirectly inhibit the growth of tumor cells. |
| CAS Registry Number: | 475207-59-1 |
| Synonyms: | ;SORAFENIB-D3;4-Methyl-3-((4-(3-pyridinyl)-2-pyrimidinyl)amino)-N-(5-(4-methyl-1H-imidazol-1-yl)-3-(trifluoromethyl)phenyl)benzamide monomethanesulfonate;N-[4-Chloro-3-(trifluoromethyl)phenyl]-N'-[4-[2-(N-methylcarbamoyl)-4-pyridyloxy]phenyl]urea Tolsylate;Sorafenib TsOH salt; |
| Molecular Formula: | C21H16ClF3N4O3·C7H8SO |
| Molecular Weight: | 637.03 |
| Molecular Structure: | 
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| Company: | Wuhan Yuancheng Gongchuang Technology Co [ China ] |
| Contact: | jorcelyn |
| Tel: | 86-027-50756069 |
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| Email: | ycsales@ycgmp.com |
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