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Spironolactone

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  Post Date: Jan 08,2015
  Expiry Date: Jan 08,2016
  Detailed Description: Cas No. :52-01-7 Quantity: 2Metric Tons
Price:1 USD Metric Tons
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Name:
Spironolactone (Related Reference)
EINECS:
200-133-6
Molecular Formula:
C24H32O4S
CAS Registry Number:
52-01-7
Synonyms:
Alderon; 3-(3-Keto-7.alpha.-acetylthio-17.beta.-hydroxy-4-androsten-17.alph a.-yl)propionic acid lactone; Uractone; Spiro(17H-cyclopenta(a)phenauthrene-17,2-(3H)-furan); Xenalon; Pregn-4-ene-21-carboxylic acid,7-(acetylthio)-17-hydroxy-3-oxo-,?- lactone,(7R,17R)-; Aldactone; 17.alpha.-Pregn-4-ene-21-carboxylic acid, 17-hydroxy-7.alpha.-mercapto-3-oxo-, .gamma.-lactone, acetate; Euteberol; Prestwick_449; Pregn-4-ene-21-carboxylic acid, 7-(acetylthio)-17-hydroxy-3-oxo-, gamma-lactone, (7alpha,17alpha)-; Spironolactone A; Urusonin; Verospirone; SC 9420; SC 15983; Spiro(17H-cyclopenta(a)phenanthrene-17,2(5H)-furan), pregn-4-ene-21-carboxylic acid deriv.; Spiro-Tablinen; Spirolang; Spironolactone [BAN:INN:JAN]; 7-alpha-Acetylthio-3-oxo-17-alpha-pregn-4-ene-21,17-beta-carbolactone; 7-alpha-(acetylthio)-17-alpha-hydroxy-3-oxopregn-4-ene-21-carboxylic acid, gamma-lactone (9CI); 496916-40-6; Spironolactonum [INN-Latin]; Aldactone A; Aldactazide (TN); Spiroctan; 3-(3-Oxo-7-alpha-acetylthio-17-beta-hydroxyandrost-4-en-17-beta-yl)propionic acid lactone; 7-(Acetylthio)-17-hydroxy-3-oxopregn-4-ene-21-carboxylic acid gamma-lactone; Pregn-4-ene-21-carboxylic acid, 7-(acetylthio)-17-hydroxy-3-oxo-, g-lactone, (7a,17a)-; Verospiron

Appearance:
White powder.
Molecular Weight:
416.57
Density:
1.24g/cm3
Boiling Point:
597℃ at 760mmHg
Melting Point:
198-207℃
Flash Point:
302.3℃
Alpha:
-37 ° (C=1, CHCL3)
Storage Temperature:
Keep container closed when not in use. Store in a cool, dry, well-ventilated area away from incompatible substances.
Refractive index:
-36 ° (C=1, CHCl3)
Solubility:
practically insoluble

Usage:
It is a synthetic 17-lactone steroid which is a renal competitive aldosterone antagonist in a class of pharmaceuticals called potassium-sparing diuretics, used primarily to treat ascites in patients with liver disease, low-renin hypertension, hypok.

  CAS Registry Number:

52-01-7
  Synonyms: ;7-alpha-Acetylthio-3-oxo-17-alpha-pregn-4-ene-21,17-beta- carbolactone; ;S-(10,13-dimethyl-3,5'-dioxo-1,2,3,4',5',6,7,8,9,10,11,12,13,14,15,16-hexadecahydro-3'H-spiro[cyclopenta[a]phenanthrene-17,2'-furan]-7-yl) ethanethioate;S-[(7R,8R,9S,10R,13S,14S,17R)-10,13-dimethyl-3,5'-dioxo-1,2,3,4',5',6,7,8,9,10,11,12,13,14,15,16-hexadecahydro-3'H-spiro[cyclopenta[a]phenanthrene-17,2'-furan]-7-yl] ethanethioate;S-[(7R,9S,10R,13S,14S,17R)-10,13-dimethyl-3,5'-dioxo-1,2,3,4',5',6,7,8,9,10,11,12,13,14,15,16-hexadecahydro-3'H-spiro[cyclopenta[a]phenanthrene-17,2'-furan]-7-yl] ethanethioate;17-Hydroxy-7-alpha-mercapto-3-oxo-17-alpha-pregn-4-ene-21-carboxylic acid-gamma-lactone-7-acetate;
  Molecular Formula: C24H32O4S
  Molecular Weight: 416.5735
  Molecular Structure: 52-01-7 Spironolactone
  Hazard Symbols:  T:Toxic;
 Xn:Harmful;
  Risk Codes: R40:;
R60:;
  Safety Description: S53:;
S22:;
S36/37/39:;
S45:;

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