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Sr9011 Sarm Series for Weight Loss 1379686-29-9
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| Post Date: | Mar 23,2017 |
| Expiry Date: | Mar 23,2018 |
| Detailed Description: |
Cas No. :1379686-29-9
Quantity: 1000Kilograms Specs:white powder Price:10 USD Kilograms Payment Method: T/T,Western Union,Moneygram, SR9011 Spec. Cas No 1379686-29-9 Formula C23H31ClN4O3S Molucelar weight 479.03524 Purity:99% Appreance:White Powder Grade: Pharmaceutical Grade Usage:For obesity, diabetes, dyslipidemia and cardiovascular disease Description SR9011 is a trifunctional methacrylate monomer that provides exceptional adhesion to metal substrates. SR9011 is recommended for use in peroxide cured coatings, sealants, and PVC-based plastisols. Usage levels of 5% to 10% by weight are recommended. SR9011 is a potent and specific synthetic REV-ERB agonist that binds to REV-ERB-α with an EC50 ~790 nM and REV-ERB-β with EC50 ~560 nM. It also has good in vivo plasma/brain exposure. The nuclear receptors REV-ERB-α and REV-ERB-β play an integral role in regulating the expression of core clock proteins, driving rhythms in activity and metabolism. Administration of SR9011 alters circadian behavior and the circadian pattern of core clock gene expression in the hypothalami of mice. The circadian expression pattern of an array of metabolic genes in the liver, skeletal muscle and adipose tissue was also altered, resulting in increased energy expenditure. Treatment of diet-induced obese mice with SR9011 decreased obesity by reducing fat mass and markedly improved dyslipidaemia and hyperglycaemia. These results indicate that synthetic REV-ERB ligands that pharmacologically target the circadian rhythm may be beneficial in the treatment of sleep disorders as well as metabolic diseases. [Function] A new compound called SR9009 increases metabolism, fat burning, and muscle growth in the lab. Scientists at The Scripps Research Institute (TSRI) have successfully tested a drug, called SR9009, in mice that kickstarts metabolism and results in increased muscle development. Essentially, it's an exercise regime in a pill. SR9009 alters the metabolic profile of skeletal muscle in a manner similar to the changes observed [in] animals [that] are endurance trained. Basically, the drug sends a signal to the muscle to tell it to modify its metabolism. |
| CAS Registry Number: | 1379686-29-9 |
| Company: | China yuancheng technoloty wuhan branch ltd. [ China ] |
| Contact: | Kathelin |
| Tel: | 86-27-6888669 |
| Fax: | |
| Email: | kathelin@chembj.com |
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