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Sunifiram

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  Post Date: Jan 18,2018
  Expiry Date: Jul 17,2018
  Detailed Description: Cas No. :314728-85-3 This enhancement by sunifiram is associated with an increase inphosphorylation of AMPAR through activation of protein kinase II(CaMKII) and an increase in phosphorylation of NMDAR through activation of protein kinase C α (PKCα). More specifically, sunifiram stimulates the glycine-binding site of NMDAR with concomitant PKCαactivation through Src kinase. Enhancement of PKCα activity triggers to potentiate hippocampal LTP through CaMKII activation. Sunifiram improves cognitive deficits via CaM kinase II andprotein kinase C activation.


  CAS Registry Number:

314728-85-3
  Synonyms: Sunifiram;DM-235;1-Benzoyl-4-(1-oxopropyl)piperazine
  Molecular Formula: C14H18N2O2
  Molecular Weight: 246.31176
  Molecular Structure: 314728-85-3 1-(4-Benzoylpiperazin-1-yl)propan-1-one

  Company: Wuhan Yuancheng Technology Co.,LTD     [ China ]        
  Contact: mariah
  Tel: 15872388127
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  Email: mariah@ycphar.com
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