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TOFACITINIB CITRATE

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  Post Date: Mar 22,2016
  Expiry Date: Sep 18,2016
  Detailed Description: Cas No. :540737-29-9 TOFACITINIB CITRATE
CAS 540737-29-9
Unstable oil
Assay: 99%
Chemical name:
(3R,4R)-1-(Cyanoacetyl)-4-methyl-N-methyl-N-1H-pyrrolo[2,3-d]pyrimidin-4-yl-3-piperidinamine 2-hydroxy-1,2,3-propanetricarboxylate
By name: CP-690550
Description
Tofacitinib, an inhibitor of Janus kinases (JAKs), is indicated for the treatment of adult patients with moderately to severely active rheumatoid arthritis who have had an inadequate response or intolerance to methotrexate. It may be used as monotherapy or in combination with methotrexate or other nonbiologic disease-modifying antirheumatic drugs (DMARDs).
Tofacitinib should not be used in combination with biologic DMARDs or potent immunosuppressants such as azathioprine and cyclosporine.

  CAS Registry Number:

540737-29-9
  Synonyms: ;Tofacitinib citrate;1-Piperidinepropanenitrile, 4-Methyl-3-(Methyl-7H-Pyrrolo[2,3-D]Pyrimidin-4-Ylamino)-Beta-Oxo-, (3R,4R)-, 2-Hydroxy-1,2,3-Propanetricarboxylate (1:1);1-PIPERIDINEPROPANENITRILE,4-METHYL-3-(METHYL-7H-PYRROLO[2,3-D]PYRIMIDIN-4-YLAMINO)-BETA-OXO-,(3R,4R)-,2-HYDROXY-1,2,3-PROPANETRICARBOXYLATE(1:1);Tasocitinib citrate;(3R,4R)-1-(Cyanoacetyl)-4-methyl-N-methyl-N-1H-pyrrolo[2,3-d]pyrimidin-4-yl-3-piperidinamine 2-hydroxy-1,2,3-propanetricarboxylate;CP 690500-10;CP 690550-10;(3R,4R)-4-Methyl-3-(methyl-7H-pyrrolo[2,3-d]pyrimidin-4-ylamino)-beta-oxo-1-piperidinepropanenitrile 2-Hydroxy-1,2,3-propanetricarboxylate;Tofacitnib Citrate;
  Molecular Formula: C16H20N6O·C6H8O7
  Molecular Weight: 504.497
  Molecular Structure: 540737-29-9 1-Piperidinepropanenitrile, 4-methyl-3-(methyl-7H-pyrrolo[2,3-d]pyrimidin-4-ylamino)-β-oxo-, (3R,4R)-, 2-hydroxy-1,2,3-propanetricarboxylate (1:1)

  Company: Koffee Pharm Co., Ltd.     [ China ]        
  Contact: kevin
  Tel: +86-21-61729394
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  Email: sales02@koffeepharm.com
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