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Terlipressin Acetate

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  Post Date: Jan 13,2013
  Expiry Date: Jan 13,2014
  Detailed Description: Cas No. :14636-12-5 Quantity: 1Kilograms
Specs:98%
Molecular Formula：
C52H74N16O15S2

Relative Molecular Mass：
1227.39 g/mol

CAS-Number：
14636-12-5


Long-term Storage：
-20 ± 5°C


Sequence：
H-Gly-Gly-Gly-Cys-Tyr-Phe-Gln-Asn-Cys-Pro-Lys-Gly-NH2 acetate salt
(Disulfide bond)

Fields of Application：

Acute variceal hemorrhage (esophageal varices)
Hepatorenal syndrome
Norepinephrine-resistant septic shock - not yet an approved application

Active Substance：
Terlipressin is a synthetic analog of vasopressin and is used as a vasoactive drug in the management of hypotension.
Terlipressin represents a prodrug, it is converted to (Lys8)- vasopressin (LVP) after removal of the N-terminal triglycine in vivo. Terlipressin has a longer duration of action and a better safety profile than the parent compound LVP

  CAS Registry Number:

14636-12-5
  Synonyms: ;n-(n-(n-glycylglycyl)glycyl)-8-l-lysinevasopressin;(2s)-1-[(4s,7s,10s,13s,16s,19s)-19-[[2-[[2-[(2-aminoacetyl)amino]acetyl]amino]acetyl]amino]-13-benzyl-10-(2-carbamoylethyl)-7-(carbamoylmethyl)-16-[(4-hydroxyphenyl)methyl]-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentazacycloicosane-4-carbonyl]-n-[(1s)-5-amino-1-(carbamoylmethylcarbamoyl)pentyl]pyrrolidine-2-carboxamide;(2S)-1-{[(4R,7S,10S,13S,16S,19R)-19-{[({[(aminoacetyl)amino]acetyl}amino)acetyl]amino}-7-(2-amino-2-oxoethyl)-10-(3-amino-3-oxopropyl)-13-benzyl-16-(4-hydroxybenzyl)-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentaazacycloicosan-4-yl]carbonyl}-N-{(2S)-6-amino-1-[(2-amino-2-oxoethyl)amino]-1-oxohexan-2-yl}pyrrolidine-2-carboxamide (non-preferred name);Terlipressin Acetate;
  Molecular Formula: C52H74N16O15S2
  Molecular Weight: 1227.3722
  Molecular Structure: 14636-12-5 Terlipressin

  Company: ISPECHEM CO.,LTD     [ China ]        
  Contact: Jeffrey
  Tel: 86-755-27802869
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  Email: jeffrey@ispechem.com
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