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Tetracaine hydrochloride

Inquiry
  Post Date: Nov 18,2017
  Expiry Date: May 17,2018
  Detailed Description: Cas No. :136-47-0 Quantity: mass in stockKilograms
Specs:white powder
Price:negotiable USD Kilograms
Payment Method: T/T, Western Union,Moneygram and Bitcoin.
Description:

Tetracaine Hydrochloride is synthesized from 4-butylaminobenzoic acid. The ethyl ester is formed through an acid-catalyzed esterification reaction. Base-catalyzed transesterification is achieved by boiling the ethyl ester of 4-butylaminobenzoic acid with excess 2-dimethylaminoethanol in the presence of a small amount of sodium ethoxide.


Applications:

Tetracaine (INN, also known as amethocaine; trade name Pontocaine. Ametop and Dicaine) is a potent local anesthetic of the ester group. It is mainly used topically in ophthalmology and as an antipruritic, and it has been used in spinal anesthesia.

In biomedical research, tetracaine is used to alter the function of calcium release channels (ryanodine receptors) that control the release of calcium from intracellular stores. Tetracaine is an allosteric blocker of channel function. At low concentrations, tetracaine causes an initial inhibition of spontaneous calcium release events, while at high concentrations, tetracaine blocks release completely.

  CAS Registry Number:

136-47-0

  Synonyms: ;Tetracaine HCl;2-dimethylaminoethyl 4-n-butylaminobenzoate hydrochloride;4-(Butylamino)benzoic acid 2-(dimethylamino)ethyl ester hydrochloride;4-(butylamino)-Benzoic acid, 2-(dimethylamino)ethyl ester, monohydrochloride;p-butylaminobenzoyl-2-dimethylaminoethanol hydrochloride;Amethocaine hydrochloride;Anethaine;Butethanol;Curtacain;Decicain;Gingicain M;Menonasal;Pantocaine;Pontocaine hydrochloride;Tonexol;Tetracaine·HCL;2-(dimethylamino)ethyl 4-(butylamino)benzoate hydrochloride (1:1);Tertracaine HCL;
  Molecular Formula: C15H25ClN2O2
  Molecular Weight: 300.8242
  Molecular Structure: 136-47-0 tetracaine hydrochloride
  Hazard Symbols:  T:Toxic;
  Risk Codes: R25:;
R36:;
R43:;
  Safety Description: S26:;
S36/37:;
S45:;

  Company: Hengyang Desen Science and Technology co., LTD.     [ China ]        
  Contact: Eric yang
  Tel: +86-189-08446905
  Fax:
  Email: Eric@desen-nutrition.com
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