Tibolone
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| Post Date: | Sep 21,2016 |
| Expiry Date: | Sep 21,2017 |
| Detailed Description: |
Cas No. :5630-53-5
Quantity: 1Kilograms Specs:alisa@pharm-china.com Price:1 USD Metric Tons Payment Method: Western Union, MoneyGram, Bank transfer, Bite Tibolone 1. Quick Details: Synonyms: TIBOLONE;LIVIELLA;LIVIAL;5(10)-ESTREN-7-ALPHA-METHYL-17-ALPHA-ETHYNYL-17-BETA-OL-3-ONE;(7A,17A)-17-HYDROXY-7-METHYL-19-NORPREGN-5(10)-EN-20-YL-3-ONE;17-hydroxy-7alpha-methyl-19-norpregn-5(10)-en-20-yn-3-one;17ALPHA-HYDROXY-7ALPHA-METHYL-19-NORPREGN-5(10)-EN-20-YN-3-ONE;19-NORPREGN-5(10)-EN-20-YN-3-ONE,17-HYDROXY-7-METHYL-, (7A,17A)- CAS: 5630-53-5 MF: C21H28O2 MW: 312.45 EINECS: 227-069-1 2. We Guarantee: a. Fast Delivery: 3 work days after received payment. b. Free Resending: For long term cooperation, we guarantee all our customers will get their stuffs. c. Long Term Cooperation Discount: 5% DISCOUNT for our regular customers. 3. 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Your requirement 4. More Information About Tibolone: Tibolone Livial/Liviella is used mainly for treatment of endometriosis, as well as hormone replacement therapy in post-menopausal women. Tibolone is a synthetic steroid hormone drug, which is fairly non-selective in its binding profile, acting as an agonist mainly at estrogen receptors, with a preference for ER alpha. Tibolone has similar or greater efficacy compared to older hormone replacement drugs, but shares a similar side effect profile. It has also been investigated as a possible treatment for female sexual dysfunction. Tibolone is a synthetic hormone-type drug which is used mainly for hormone replacement therapy in post-menopausal women. It is a synthetic steroid that has the same activity as the female sex hormones estrogen and progesterone and the androgen testosterone. Tibolone helps restore hormonal balance in the body. When estrogen levels are low tissues can slowly degenerate, as is experienced during menopause. In addition, low levels of estrogen can cause distressing symptoms such as hot flushes, night sweats, mood swings, reduced sex drive and vaginal dryness. Tibolone is broken down into three compounds which act in a similar way to the natural estrogen and progesterone found in the body. It restores plasma endorphin level in post-menopausal women and acts centrally to affect the thermo-regulatory system. a.Tibolone Acetate prevents bone loss and reduces spinal fractures . One uncontrolled English study has suggested that Tibolone Acetate increases breast cancer risk but better quality placebo controlled randomised trials do not show that breast cancer rates in healthy women are changed by Tibolone Acetate . Tibolone Acetate does not increase breast density . Tibolone Acetate may interfere with the effectiveness of breast cancer therapies and its use is contraindicated in women with breast cancer . b.Regular mammograms and breast examination are advisable for all women. Tibolone Acetate decreases total and LDL cholesterol and triglyceride levels. However, it also decreases HDL cholesterol. The impact of these changes are not clear. Recent research suggests that Tibolone Acetate increases the risk of stroke [5]. This risk is mainly seen in women over 60 years of age. The increase among women in their 50s is 4 extra cases per 1000 and among women in their 60s, an extra 13 cases per 1000 women. Tibolone Acetate should not be used for cardiovascular protection. Few data are available with regard to thrombosis risk are available and the outcomes are inconclusive. c.Although the menopause is a generic physiologic event, its biology is variable and specific to a given individual. Genetically determined distribution and polymorphism of relevant hormone receptors, enzymes, and various cofactors are the biologic mechanisms controlling an individual's clinical response to endogenous and prescribed hormones. Advances in molecular biology have led to the development of newer pharmacologic agents that are tailored to meet specific therapeutic objectives, based on the hormonal biology of relevant organs. Tibolone Acetate, an analogue of the progestin, norethynodrel, is a drug with tissue-specific effects on receptors and enzymes that influences the synthesis and metabolism of endogenous estrogen, progesterone, and androgen. This is achieved via the intestinal bioconversion of Tibolone Acetate into metabolites that have tissue-specific agonistic and/or antagonistic estrogenic (3alpha and 3beta hydroxyTibolone Acetate) and progestogenic/androgenic (delta4 Tibolone Acetate) properties. d.The postmenopausal synthesis and metabolism of estrogen and androgen are briefly reviewed with particular reference to sex steroid activity in various target organs. On the basis of this hormonal physiology, the clinical utility of Tibolone Acetate is reviewed as a therapeutic agent for the treatment of the symptomatic menopause. The effects of Tibolone Acetate on bone health and osteoporosis, cardiovascular disease, the breast, and the endometrium are summarized, and its role in clinical practice is reviewed. 5. Key words: Buy Tibolone, Tibolone raw powder, Tibolone anabolic steroid powder, Tibolone price, anabolic steroid powder Tibolone, Tibolone COA, Tibolone manufacturer, Tibolone powder, body building steroid Tibolone, body building supplement Tibolone, Tibolone for muscle gaining, Tibolone for fat burning, Tibolone injection, Tibolone semi-finished injection, Tibolone steroid raw, Tibolone raw material, Tibolone fine powder, high purity Tibolone powder, Tibolone 99% assay, Tibolone CAS, Tibolone HPCL, Tibolone factory 6. Seller's Information: Company: Shanghai Yijing Pharmaceutical Co., Ltd Mob: +OO86-13O26163653 7. How to place an order: Send me an email at the address above, tell me product name and quantity. |
| CAS Registry Number: | 5630-53-5 |
| Synonyms: | ;-TIBOLONE;LIVIELLA;LIVIAL;5(10)-ESTREN-7-ALPHA-METHYL-17-ALPHA-ETHYNYL-17-BETA-OL-3-ONE;(7A,17A)-17-HYDROXY-7-METHYL-19-NORPREGN-5(10)-EN-20-YL-3-ONE;17-hydroxy-7alpha-methyl-19-norpregn-5(10)-en-20-yn-3-one;17ALPHA-HYDROXY-7ALPHA-METHYL-19-NORPREGN-5(10)-EN-20-YN-3-ONE;19-NORPREGN-5(10)-EN-20-YN-3-ONE,17-HYDROXY-7-METHYL-, (7A,17A)-;(7alpha,8xi,13xi,17beta)-17-ethynyl-17-hydroxy-7-methylestr-5(10)-en-3-one;(7alpha,17beta)-17-ethynyl-17-hydroxy-7-methylestr-5(10)-en-3-one; |
| Molecular Formula: | C21H28O2 |
| Molecular Weight: | 312.4458 |
| Molecular Structure: | 
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| Hazard Symbols: |  N:; |
| Risk Codes: | 51/53:; |
| Safety Description: | 22-24/25-61:; |
| Company: | Shanghai Yijing Pharmaceutical Co., Ltd [ China ] |
| Contact: | Alisa |
| Tel: | +86-130-26163653 |
| Fax: | |
| Email: | alisa@pharm-china.com |
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