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Top Quality Anesthesia Medicine Baclofen Factory Supplying
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| Post Date: | Jun 09,2015 |
| Expiry Date: | Jun 08,2016 |
| Detailed Description: |
Cas No. :1134-47-0
Quantity: 1000Metric Tons Specs:1kg/ Foil bay or as custome's requirement Price:1 USD Kilograms Payment Method: T/T, Western Union, Money Gram Product Name: Baclofen Tag: gamma-aminobutyric acid, GABA, Kemstro,Lioresal,Liofen,Gablofen,Lyflex,Beklo,Baclosan 1. Basic Information: Product Name Baclofen Synonym Kemstro,Lioresal,Liofen,Gablofen,Lyflex,Beklo,Baclosan CAS 1134-47-0 MF C10H12ClNO2 MW 213.66 EINECS 214-486-9 Assay 99% Quality Standards Enterprise Standard/Pharma Grade Appearance White powder Package 25kg/Drum Place of Origin China Brand Name SMQ Certification ISO9001, ISO14000, KOSHER Model Number 1134-47-0 MOQ 1kg Ref. Price USD 200/kg Packaging Details 25kg/Drum, 1kg/bag Delivery Time 1-2 days Payment Terms T/T, Western union, Money gram Supply Ability 500000 T/Month 2. Quick View: (1) Baclofen (brand names Kemstro, Lioresal, Liofen, Gablofen, Lyflex, Beklo and Baclosan) is a derivative of gamma-aminobutyric acid (GABA). It is primarily used to treat spasticity and is in the early research stages for use for the treatment of alcoholism. It is also used by compounding pharmacies in topical pain creams as a muscle relaxant. (2) It is an agonist for the GABAB receptors. Its beneficial effects in spasticity result from actions at spinal and supraspinal sites. Baclofen can also be used to treat hiccups. (3)A beneficial property of baclofen is that tolerance does not seem to occur to a significant degree — baclofen retains its therapeutic anti-spasmodic effects even after many years of continued use. Newer studies, however, indicate that tolerance may develop in some patients receiving intrathecal baclofen treatment. 3. Medical uses: Baclofen is primarily used for the treatment of spastic movement disorders, especially in instances of spinal cord injury, cerebral palsy, and multiple sclerosis. Its use in people with stroke or Parkinson's disease is not recommende. 4. Mechanism of action: Baclofen produces its effects by activating the GABAB receptor, similar to the drug GHB which also activates this receptor and shares some of its effects. However, baclofen does not have significant affinity for the GHB receptor, and has no known abuse potential. The modulation of the GABAB receptor is what produces baclofen's range of therapeutic properties. |
| CAS Registry Number: | 1134-47-0 |
| Synonyms: | ;(+/-)-beta(Aminomethyl)-4-chlorobenzenepropanoic acid, Lioresal;4-amino-3-(4-chlorophenyl)butyric acid;Atrofen;beta-(4-chlorophenyl)gaba;beta-(4-chlorophenyl)-gamma-aminobutyric acid;ba 34647;baclon;beta-(aminomethyl)-4-chlorobenzenepropanoic acid;beta-(aminomethyl)-p-chlorohydrocinnamic acid;c 34647ba;ciba 34,647-ba;Lioresal;gamma-amino-beta-(p-chlorophenyl)butyric acid;4-amino-3-(4-chlorophenyl)butanoic acid;(3S)-4-amino-3-(4-chlorophenyl)butanoic acid; |
| Molecular Formula: | C10H12ClNO2 |
| Molecular Weight: | 213.6608 |
| Molecular Structure: | 
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| Hazard Symbols: |  T:Toxic; |
| Risk Codes: | R61:; R25:; R36/37/38:; R42/43:; |
| Safety Description: | S52:; S22:; S36/37/39:; S45:; |
| Company: | Hubei Yuchen Pharma Co,. Ltd [ China ] |
| Contact: | dingjianhui |
| Tel: | 86-027-50756254 |
| Fax: | 86-027-68886696 |
| Email: | anastasia@chembj.com |
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