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Top Quality Anesthesia Medicine Fluticasone Propionate Factory Supplying
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| Post Date: | Jun 09,2015 |
| Expiry Date: | Jun 08,2016 |
| Detailed Description: |
Cas No. :80474-14-2
Quantity: 1000Metric Tons Specs:1kg/ Foil bay or as custome's requirement Price:1 USD Kilograms Payment Method: T/T, Western Union, Money Gram Product Name: Fluticasone Propionate Tag: Flutide,Fluticasone Propionate 1. Basic Information: Product Name Fluticasone Propionate Synonym Flutide,CCI18781,Fluticasone17-Propionate CAS 80474-14-2 MF C25H31F3O5S MW 500.57 Assay 99% Quality Standards Enterprise Standard/Pharma Grade Appearance White powder Package 1kg/Foil bag Place of Origin China Brand Name SMQ Certification ISO9001, ISO14000, KOSHER Model Number 80474-14-2 MOQ 10g Ref. Price USD 15/g Packaging Details 1kg/Foil bag, 500g/Foil bag, 100g/Foil bag, 10g/Foil bag Delivery Time 1-2 days Payment Terms T/T, Western union, Money gram Supply Ability 500 T/Month 2. Quick View: Fluticasone Propionate belongs to a class of drugs known as corticosteroids, specifically glucocorticoids, which are hormones that predominantly affect the metabolism of carbohydrates and, to a lesser extent, fat and protein. It is used to treat asthma, allergic rhinitis, nasal polyps, various skin disorders and Crohn’s disease and ulcerative colitis. It is also used to treat eosinophilic esophagitis. 3. Pharmacology: Fluticasone propionate is a highly selective agonist at the glucocorticoid receptor with negligible activity at androgen, estrogen, or mineralocorticoid receptor thereby producing anti-inflammatory and vasoconstriction effects. It has been shown to have a wide range of inhibitory effects on multiple cell types (e.g. mast cell, eosinophil, neutrophil, macrophages, and lymphocytes) and mediators (e.g. histamine, eicosanoids, leukotrienes, and cytokines) involved in inflammation. Fluticasone propionate is stated to exert a topical effect on the lungs without significant systemic effects at usual doses, due to its low systemic bioavailability. 4. Medical uses & administration: (1) Asthma: Fluticasone is used by powder or aerosol inhalation for the prophylaxis of asthma. Typical initial doses in the UK range from 100 to 250 micrograms twice daily in mild asthma up to 1 mg twice daily in severe asthma, adjusted according to response. Children over 4 years of age may be given initial doses of 50 to 100 micrograms twice daily, increased to 200 micrograms twice daily if necessary. The drug may also be given via a nebuliser in severe chronic asthma. Usual adult doses are 0.5 to 2 mg twice daily. Children aged 4 to 16 years may be given 1 mg twice daily. (2) Allergic rhinitis: Nasal spray preparation of Fluticasone propionate is used in the prophylaxis and treatment of allergic rhinitis. The usual dose is 100 micrograms into each nostril once daily, increased if necessary to 100 micrograms into each nostril twice daily. Children over 4 years of age may be given half these doses. (3) Nasal polyps: Fluticasone propionate nasal drops are used in the treatment of nasal polyps. 200 micrograms should be instilled into each nostril once or twice daily for at least 4 to 6 weeks. (4) Other: Creams and ointments containing 0.05% and 0.005% Fluticasone propionate, respectively, are available and applied topically in the treatment of various skin disorders. It can be given orally in the treatment of Crohn’s disease and ulcerative colitis. Some benefit was also reported in coeliac disease. The dose is 5 mg four times daily but some consider higher doses necessary. |
| CAS Registry Number: | 80474-14-2 |
| Synonyms: | ;S-Fluoromethyl-6alpha,9alpha-difluoro-11beta-hydroxy-16alpha-methyl-3-oxo-17alpha-propionyloxyandrosta-1,4-diene-17beta-carbothioate; (6a,11b,16a,17a)-6,9-Difluoro-11-hydroxy-16-methyl-3-oxo-17-(1-oxopropoxy)androsta-1,4-diene-17-carbothioic acid S-(fluoromethyl) ester;(6alpha,8xi,11beta,16alpha,17alpha)-6,9-difluoro-17-{[(fluoromethyl)sulfanyl]carbonyl}-11-hydroxy-16-methyl-3-oxoandrosta-1,4-dien-17-yl propanoate;(6alpha,11beta,16alpha,17alpha)-6,9-difluoro-17-{[(fluoromethyl)sulfanyl]carbonyl}-11-hydroxy-16-methyl-3-oxoandrosta-1,4-dien-17-yl propanoate;S-(fluoromethyl) (6alpha,11beta,16alpha,17alpha)-6,9-difluoro-11,17-dihydroxy-16-methyl-3-oxoandrosta-1,4-diene-17-carbothioate; |
| Molecular Formula: | C22H27F3O4S |
| Molecular Weight: | 444.5076 |
| Molecular Structure: | 
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| Safety Description: | S22:; S24/25:; |
| Company: | Hubei Yuchen Pharma Co,. Ltd [ China ] |
| Contact: | dingjianhui |
| Tel: | 86-027-50756254 |
| Fax: | 86-027-68886696 |
| Email: | anastasia@chembj.com |
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